Cell Cycle and Apoptosis Flashcards
Stages of the cell cycle
S phase, M Phase
Stages of Mitosis
Interphase, Prophase, Metaphase, Anaphase, Telophase
Major processes in M Phase
Mitosis and Cytokineses
Considered the engine of the cell cycle
Cyclin-dependent Kinases
Considered the gear box of the cell cycle
Cyclins
In which phase of the cell cycle are CDKs synthesized?
Late G1
Late in G1, CDKs phosphorylate and activate transcription factors that encode component of which complex?
S phase CDK complex
G1 CDKs phosphorylation of a target inhibitor would: a. target it for degradation b. target it for promotion
A. Target for degradation
The release of this Kinase marks the onset of S-phase
S-phase CDK
S-phase CDKs phosphorylate which complex? Ths results to?
pre-replication complexes. This results to one round of replication initiation.
In which phase of the cell cycle are mitotic CDK complexes produced?
S-Phase and G2
The activation of this Kinase marks the onset of the M-phase. This results to?
Mitotic CDK. Initiation of Mitosis.
This complex when activated targets cohesin for degradation allowing the segregation of sister chromatids and eventually, the degradation of mitotic CDKs
Anaphase Promoting Complex (APC)
In this checkpoint, the cell checks the condition of the DNA
Between G1 and S
In this checkpoint, the cell checks if there are enough materials for cell division
G2 and M
