Basic transcriptional control mechanisms Flashcards
This type of response in gene expression is DEPENDENT on the continued presence of inducing signal
Type A
This type of response in gene expression is TRANSIENT despite the continued presence of the signal
Type B
This type of response in gene expression PERSISTS and is IRREVERSIBLE even after the termination of the signal
Type C
These regulators in transcription influence gene expression only on the same chromosome
Cis-acting elements
This is a group of prokaryotic genes in a linear array involved in a metabolic pathway
Operon
What is the Negative regulator of the Lac Operon? What is its Positive regulator?
Negative: Lac I
Positive: CAP-cAMP
True or False: >2% of the DNA is coding
False
The activated Lac Operon stimulates the activity of which enzymes?
Beta Galactosidase and Lactase Permease
These genes in eukaryotes are ‘constitutively’ expressed
Unregulated genes
This is the region of DNA that signals for initiation, elongation and termination . It produces pre-mRNA from the template strand
Transcription Unit
DNA region where RNA polymerase will bind to initiate transcription
Promoter Region
TATA box in prokaryotes
Pribnow Box
TATA box in eukaryotes
Hogness Box
Position of TATA box in eukaryotes
-25
POsition of TATA box in prokaryotes
-10
Which of the following proteins are associated with Initiating the binding to the promoter site? Which is for termination?
A. Sigma Factor
B. Rho Factor
A. B. Respectively
Aside from identifying the part of DNA to start transcription at, what is the other purpose of promoters?
Frequency of RNA synthesis
DNA sequences that facilitate transcription (different from promoters)
Enhancers
The only eukaryoic transcription factor that binds to DNA
TFIID
Transcription factors that stabilize the initiation complex
TFIIA and B
Transcription factor structurally and functionally similar to the Sigma Factor
TFIIF
Components of TFIID
TBP and TAF
