Cell Cycle Flashcards
0
Q
Regulation of the Cell Cycle
A
G1: prolonged in stable or permanent cells
: rapid (embryonic cells) or non-existent
1
Q
Cytokinesis happens in…
Facilitated by?
A
Late Anaphase
Actin
2
Q
CDK + Cyclin
A
MPF Maturation Promoting Factor
3
Q
Cyclin
A
Destruction is controlled by ubiquination
4
Q
CDK regulation
A
Phosphorylation
Cyclin synthesis and destruction
5
Q
CKI
A
Regulated by G1-S Transition
6
Q
p16 is an inhibitor
Mutation leads to…
A
TUMORS
7
Q
Apoptosis vs Necrosis
Apoptosis
- planned death
- shrinking of cell
- intracellular components hidden from immune components (no inflammation)
A
Necrosis
- accidental death
- includes swelling of the cell
- inflammation
8
Q
Why should a cell commit suicide?
A
For proper development
To destroy cells (cells infected with viruses)
9
Q
DNA damage
A
Happens in S and G2
10
Q
Where can apoptosis be encountered?
A
Growth of embryo
AIDS
11
Q
True or False
No apoptosis at +4 degrees Celsius
A
True
Apoptosis is an enzyme dependent process
No enzyme at 4’C
