Cell Cycle Flashcards
A cell’s DNA, packaged as a double-stranded DNA molecule
Genome
Number of chromosomes in the somatic cells of the human body
46
Number of chromosomes that human gametes have
23
A configuration of two matched or homologous sets of chromosomes
Diploid
Human cells that contain one set of chromosomes
Gametes or sex cells (eggs and sperm)
Gametes are designated as _____.
1n or haploid
A diploid cell containing matched pairs of chromosomes created upon fertilization; carry the same genes; one set from each parent
Homologous chromosomes
Homologous chromosomes are the same length and have specific nucleotides segments or _____ exactly the same location or _____.
genes; locus
Breadlike, histone DNA complex
Nucleosome
Compose the chromosomes
Two linked sister chromatids
An ordered series of events involving cell growth and cell division that produces two new daughter cells
Cell cycle
Period of growth; where 90% of the time is spent; the cell undergoes normal growth process while also preparing for cell division; metabolic phase of the cell; the cell obtains nutrients and metabolizes them
Interphase
The first stage of interphase; little change is visible; the cell is quite active at the biochemical level; the cell is accumulating the building blocks of chromosomal DNA
G1 phase (first gap)
DNA replication can proceed through the mechanisms that result in the formation of identical pairs of DNA molecules ; sister chromatids are firmly attached to the centromeric region.
S phase (synthesis of DNA)
The apparatus that orchestrates the movement of chromosomes during mitosis
Mitotic spindle
Rod-like objects where the centrosomes are associated with; positioned at right angles to each otherl help organize cell division
Centrioles
In this phase, the cell replenishes its energy, stores and synthesizes proteins necessary for chromosome manipulation and movement
G2 phase (second gap)
The first portion of the mitotic phase; nuclear division
Karyokinesis
Eukaryotic cell nucleus splits in two, followed by division of the present cell into two daughter cells.
Mitosis
The first phase of mitosis; the nuclear envelope starts to dissociate into small vesicles, and the membranous organelles fragment and disperse toward the periphery of the cell; chromosomes condense and become visible; spindle fibers emerge from the centrosomes; nuclear envelope breaks down; nucleolus disappears
Prophase
The first change phase; chromosomes continue to condense; kinetochores appear at the centromeres; mitotic spindle microtubules attach to kinetochores; centrosomes move toward opposte poles
Prometaphase
A protein structure developed by each sister chromatid in its centromeric region
Kinetochore
Spindle fibers that do not engage the chromosomes
Polar microtubules
The change phase; mitotic spindle is fully developed, centrosomes are at opposite poles of the cell; chromosomes are lined up at the metaphase plate; each sister chromatid is attached to a spindle fiber originating from opposite poles
Metaphase
The equatorial plane, roughly midway between the two poles of the cell
Metaphase plate
Upward phase; cohesin proteins binding the sister chromatids break down; sister chromatids (now called chromosomes) are pulled toward opposite poles; non-kinetochore spindle fibers lengthen, elongating the cell
Anaphase
The distance phase; chromosomes arrive at opposite poles and begin to decondense; nuclear envelope material surrounds each set of chromosomes; the mitotic spindle breaks down
Telophase
Sometimes viewed as the second main stage of the mitotic phase, during which cell division is completed via the physical separation of the cytoplasmic components into two daughter cells; aka “cell motion”; splits the parent cell into daughter cells
Cytokinesis
A fissure formed when actin filaments pull the equator of the cell inward (in animal cells)
Cleavage furrow
A vesical structure formed when Golgi vesicles are transported on microtubules during telophase
Phragmoplast