Cell Ageing and Death Flashcards
Does necrosis require energy?
no
Is necrosis ever physiological?
no
What happens in coagulative necrosis?
preservation of cell outline
Where does coagulative necrosis often take place?
heart - myocardium infarction
Liquefactive necrosis is often seen as what?
puss
Where on the body is liquefactive necrosis often seen?
brain
What is apoptosis?
programmed cell death in response to specific signals
Does apoptosis require energy?
yes
Can apoptosis be physiological?
yes
Give a few examples of when pathological apoptosis occurs?
radiation, chemotherapy, cancers
What is the extrinsic pathway?
death receptor initiated pathway
Give an example of a death receptor
Tumour necrosis factor
Intrinsic pathway is what sort of pathway?
mitochondrial
What effect does it have on mitochondria?
increases permeability
What is pyknosis?
cells shrinking
