CBC And Anemias (Exam 2) Flashcards

1
Q

What 3 things do you look at on a CBC to decide if there is an anemia?

A
    • RBC
    • HgB
    • HcT
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2
Q

What does the following indicate?

    • Normal RBC
    • Normal HgB
    • Normal HcT
A

Normal not anemic

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3
Q

What does the following indicate?

    • High RBC
    • High HgB
    • High HcT
A

Polycythemia

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4
Q

What does the following indicate?

    • Low RBC
    • Low HgB
    • Low HcT
A

Anemia

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5
Q

Anemias are classified by what 2 things?

A

Cell size and cell color

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6
Q

RBC color is really a measure of ______ content.

A

Hemoglobin

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7
Q

How do you determine cell size and color?

A

RBC Indices

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8
Q

An RBC Indices consists of what 3 things?

A
    • McV
    • McH
    • McHc
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9
Q

Which RBC Indices dictates cell size?

A

McV = cell size

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10
Q

Which RBC Indices dictates cell color?

A

McH and McHc = color

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11
Q

What anemia is associated with the following:

– Decreased McV

A

Microcytic anemia

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12
Q

What anemia is associated with the following:

– Normal McV

A

Normocytic anemia

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13
Q

What anemia is associated with the following:

– Increased McV

A

Macrocytic anemia

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14
Q

What anemia is associated with the following:

– Decreased McH (McHc)

A

Hypochromic anemia

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15
Q

What anemia is associated with the following:

– Normal McH (McHc)

A

Normochromic

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16
Q

What anemia is associated with the following:

– Increased McH (McHc)

A

Hyperchromic anemia

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17
Q

What is the most common anemia in the world?

A

IDA

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18
Q

What is the most common anemia based on cell size?

A

Microcytic

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19
Q

What is the most common microcytic anemia?

A

IDA

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20
Q

What is the most common etiology of IDA?

A

CBL

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21
Q

What is the most common cause of CBL?

A

GI tract bleeding

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22
Q

What RBC Indices would indicate microcytic hypochromic anemias?

A

Decreased McV, McH, McHc

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23
Q

What are 4 causes of Microcytic Hypochromic anemias?

A
    • IDA
    • CBL
    • Thalassemia
    • Anemia of chronic disease
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24
Q

What is the most common cause of Microcytic Hypochromic anemia?

A

IDA

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25
Q

What are the 3 Iron parameters?

A
    • TIBC
    • Iron
    • Ferritin
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26
Q

What Iron Parameter is the best to differentiate Microcytic Hypochromic anemias?

A

TIBC

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27
Q

IDA has _____ TIBC?

A

Increased

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28
Q

CBL has ______ TIBC

A

Increased

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29
Q

ACD has _____ TIBC

A

Decreased

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30
Q

Thalassemia has _______ TIBC

A

Normal

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31
Q

ARD has _____ TIBC

A

Decreased

32
Q

What RBC Indices would indicate Normocytic Normochromic anemias?

A
    • Normal McV
    • Normal McH
    • Normal McHc
33
Q

What are 4 causes of Normocytic Normochromic anemias?

A
    • Hemolytic / Sickle Cell
    • Acute blood loss
    • Aplastic
    • Anemia of chronic disease
34
Q

What RBC Indices would indicate Macrocytic Normochromic anemias?

A
    • Increased McV
    • Normal McH
    • Normal McHc
35
Q

What RBC Indices would indicate Macrocytic Hyperchromic anemias?

A
    • Increased McV
    • Increased McH
    • Increasead McHc
36
Q

Microcytic Hyperchromic anemia is aka?

A

Polychromasia

37
Q

What are 4 causes of Macrocytic Normochromic/Hyperchromic anemias?

A
    • B12 deficiency
    • Folic acid deficiency
    • Liver disease
    • Alcoholism
38
Q

2 causes of Megaloblastic anemias?

A

B12 and Folic acid deficiency

39
Q

2 causes of Nonmegaloblastic anemias?

A

Liver disease and alcoholism

40
Q

Which is the most common Macrocytic Anemia:

– Megaloblastic or Nonmegaloblastic?

A

Megaloblastic

41
Q

If it is a B12 deficiency then it is most likely due to what?
– And called what?

A
    • Lack of Intrinsic Factor

- - Pernicious Anemia

42
Q

1/4 of patients with ______ anemia die of stomach cancer.

A

Pernicious anemia

43
Q

Normal WBC count is 5-10.

– Less than 5 most commonly due to??????

A

Viral infection

44
Q

Normal WBC count is 5-10

– 10-18 WBC count most commonly due to???????

A

Bacterial infection/inflammation

45
Q

Normal WBC count is 5-10

– 20 -30 WBC count with S/S of abdominal complaint is most likely due to what 2 things?

A
    • Peritonitis

- - Diverticulitis

46
Q

30 - 50 WBC count is most likely due to what 2 things?

A

Leukemoid reaction or Leukemia

– if Leukemia then most likely Chronic

47
Q

> 50 WBC count is most likely what?

A

Leukemia

48
Q

Sets primarily respond to…

A

Bacteria

49
Q

Bands primarily respond to….

A

Bacteria

50
Q

Lymphocytes primarily respond to…

A

Virus

51
Q

Eosinophils primarily respond to what 2 things?

A

Parasites and Allergies

52
Q

Basophils primarily respond to…

A

Hypersensitivites/Allergies

53
Q

Monocytes respond to help…

A

Neutrophils

54
Q

What is an increase in immature cells called?

A

Shift to the left

55
Q

Leukemias are classified by what 3 things?

A
    • Predominate cell
    • Immature cell
    • Cell lineage out of control
56
Q

Presence of Blasts and/or Pro’s make _____ Leukemia.

A

Acute

57
Q

Absence of Blasts and/or Pro’s make _____ Leukemia.

A

Chronic

58
Q

What 4 things and stem cells are bone marrow cells and should remain in bone marrow?

A
  • -Metas
    • Myelos
    • Pro’s
    • Blasts
59
Q

Metas, Myelos, Pro’s and Blasts listed on a differential belong to _______ unless they are designated by a letter.

A

Neutrophils/Segs

60
Q

L-Blasts will become…

A

Lymphocytes

61
Q

L-Pro’s will become…

A

Lymphocytes

62
Q

B-Blasts will become…

A

Basophils

63
Q

B-Metas will become…

A

Basophils

64
Q

Greater than 50,000 WBC

—- Yada, Yada, Yada,….5 metas, 5 myelo, 5 pro’s and 5 blasts = ??????

A

Acute myelocytic leukemia

65
Q

Greater than 50,000 WBC

—- Yada, Yada, Yada,….5 E-metas, 5 E-myelo, 5 E-pro’s and 5 E-blasts = ??????

A

Acute eosinophilic leukemia

66
Q

Greater than 50,000 WBC

—- Yada, Yada, Yada,….5 L-metas, 5 L-myelo, 5 L-pro’s and 5 L-blasts = ??????

A

Acute lymphocytic leukemia

67
Q

Greater than 50,000 WBC’s is….

A

Leukemia

68
Q

42 WBC

Yada, Yada, Yada, predominate Segs is _____ or _____

A

– Neutorphilic Leukemoid reaction

– Chronic myelocytic leukemia

69
Q

How do you differentiate between Neutrophilic Leukemoid reaction and CML?

A
    • Bone marrow biopsy
    • Philadelphia chromosome
    • Alkaline phosphatase
70
Q

Neutorphilic Leukemoid reactions resemble what leukemia?

A

CML

71
Q

Lymphocytic Leukemoid reactions resemble what leukemia?

A

CLL

72
Q

42 WBC

Yada, Yada, Yada……5 blasts

A

Acute myelocytic leukemia

73
Q

42 WBC

Yada, Yada, Yada,….5 L-blasts

A

Acute lymphocytic leukemia

74
Q

Presence of what cells equals Hodgkin’s Lymphoma?

A

Reed Sternberg cells (via lymph nodes biopsy)

75
Q

Malignant proliferation of what cells is multiple myeloma?

A

Plasma cells