CBC And Anemias (Exam 2) Flashcards

1
Q

What 3 things do you look at on a CBC to decide if there is an anemia?

A
    • RBC
    • HgB
    • HcT
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2
Q

What does the following indicate?

    • Normal RBC
    • Normal HgB
    • Normal HcT
A

Normal not anemic

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3
Q

What does the following indicate?

    • High RBC
    • High HgB
    • High HcT
A

Polycythemia

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4
Q

What does the following indicate?

    • Low RBC
    • Low HgB
    • Low HcT
A

Anemia

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5
Q

Anemias are classified by what 2 things?

A

Cell size and cell color

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6
Q

RBC color is really a measure of ______ content.

A

Hemoglobin

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7
Q

How do you determine cell size and color?

A

RBC Indices

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8
Q

An RBC Indices consists of what 3 things?

A
    • McV
    • McH
    • McHc
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9
Q

Which RBC Indices dictates cell size?

A

McV = cell size

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10
Q

Which RBC Indices dictates cell color?

A

McH and McHc = color

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11
Q

What anemia is associated with the following:

– Decreased McV

A

Microcytic anemia

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12
Q

What anemia is associated with the following:

– Normal McV

A

Normocytic anemia

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13
Q

What anemia is associated with the following:

– Increased McV

A

Macrocytic anemia

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14
Q

What anemia is associated with the following:

– Decreased McH (McHc)

A

Hypochromic anemia

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15
Q

What anemia is associated with the following:

– Normal McH (McHc)

A

Normochromic

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16
Q

What anemia is associated with the following:

– Increased McH (McHc)

A

Hyperchromic anemia

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17
Q

What is the most common anemia in the world?

A

IDA

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18
Q

What is the most common anemia based on cell size?

A

Microcytic

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19
Q

What is the most common microcytic anemia?

A

IDA

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20
Q

What is the most common etiology of IDA?

A

CBL

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21
Q

What is the most common cause of CBL?

A

GI tract bleeding

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22
Q

What RBC Indices would indicate microcytic hypochromic anemias?

A

Decreased McV, McH, McHc

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23
Q

What are 4 causes of Microcytic Hypochromic anemias?

A
    • IDA
    • CBL
    • Thalassemia
    • Anemia of chronic disease
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24
Q

What is the most common cause of Microcytic Hypochromic anemia?

A

IDA

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25
What are the 3 Iron parameters?
- - TIBC - - Iron - - Ferritin
26
What Iron Parameter is the best to differentiate Microcytic Hypochromic anemias?
TIBC
27
IDA has _____ TIBC?
Increased
28
CBL has ______ TIBC
Increased
29
ACD has _____ TIBC
Decreased
30
Thalassemia has _______ TIBC
Normal
31
ARD has _____ TIBC
Decreased
32
What RBC Indices would indicate Normocytic Normochromic anemias?
- - Normal McV - - Normal McH - - Normal McHc
33
What are 4 causes of Normocytic Normochromic anemias?
- - Hemolytic / Sickle Cell - - Acute blood loss - - Aplastic - - Anemia of chronic disease
34
What RBC Indices would indicate Macrocytic Normochromic anemias?
- - Increased McV - - Normal McH - - Normal McHc
35
What RBC Indices would indicate Macrocytic Hyperchromic anemias?
- - Increased McV - - Increased McH - - Increasead McHc
36
Microcytic Hyperchromic anemia is aka?
Polychromasia
37
What are 4 causes of Macrocytic Normochromic/Hyperchromic anemias?
- - B12 deficiency - - Folic acid deficiency - - Liver disease - - Alcoholism
38
2 causes of Megaloblastic anemias?
B12 and Folic acid deficiency
39
2 causes of Nonmegaloblastic anemias?
Liver disease and alcoholism
40
Which is the most common Macrocytic Anemia: | -- Megaloblastic or Nonmegaloblastic?
Megaloblastic
41
If it is a B12 deficiency then it is most likely due to what? -- And called what?
- - Lack of Intrinsic Factor | - - Pernicious Anemia
42
1/4 of patients with ______ anemia die of stomach cancer.
Pernicious anemia
43
Normal WBC count is 5-10. | -- Less than 5 most commonly due to??????
Viral infection
44
Normal WBC count is 5-10 | -- 10-18 WBC count most commonly due to???????
Bacterial infection/inflammation
45
Normal WBC count is 5-10 | -- 20 -30 WBC count with S/S of abdominal complaint is most likely due to what 2 things?
- - Peritonitis | - - Diverticulitis
46
30 - 50 WBC count is most likely due to what 2 things?
Leukemoid reaction or Leukemia -- if Leukemia then most likely Chronic
47
> 50 WBC count is most likely what?
Leukemia
48
Sets primarily respond to...
Bacteria
49
Bands primarily respond to....
Bacteria
50
Lymphocytes primarily respond to...
Virus
51
Eosinophils primarily respond to what 2 things?
Parasites and Allergies
52
Basophils primarily respond to...
Hypersensitivites/Allergies
53
Monocytes respond to help...
Neutrophils
54
What is an increase in immature cells called?
Shift to the left
55
Leukemias are classified by what 3 things?
- - Predominate cell - - Immature cell - - Cell lineage out of control
56
Presence of Blasts and/or Pro's make _____ Leukemia.
Acute
57
Absence of Blasts and/or Pro's make _____ Leukemia.
Chronic
58
What 4 things and stem cells are bone marrow cells and should remain in bone marrow?
- -Metas - - Myelos - - Pro's - - Blasts
59
Metas, Myelos, Pro's and Blasts listed on a differential belong to _______ unless they are designated by a letter.
Neutrophils/Segs
60
L-Blasts will become...
Lymphocytes
61
L-Pro's will become...
Lymphocytes
62
B-Blasts will become...
Basophils
63
B-Metas will become...
Basophils
64
Greater than 50,000 WBC | ---- Yada, Yada, Yada,....5 metas, 5 myelo, 5 pro's and 5 blasts = ??????
Acute myelocytic leukemia
65
Greater than 50,000 WBC | ---- Yada, Yada, Yada,....5 E-metas, 5 E-myelo, 5 E-pro's and 5 E-blasts = ??????
Acute eosinophilic leukemia
66
Greater than 50,000 WBC | ---- Yada, Yada, Yada,....5 L-metas, 5 L-myelo, 5 L-pro's and 5 L-blasts = ??????
Acute lymphocytic leukemia
67
Greater than 50,000 WBC's is....
Leukemia
68
42 WBC | Yada, Yada, Yada, predominate Segs is _____ or _____
-- Neutorphilic Leukemoid reaction -- Chronic myelocytic leukemia
69
How do you differentiate between Neutrophilic Leukemoid reaction and CML?
- - Bone marrow biopsy - - Philadelphia chromosome - - Alkaline phosphatase
70
Neutorphilic Leukemoid reactions resemble what leukemia?
CML
71
Lymphocytic Leukemoid reactions resemble what leukemia?
CLL
72
42 WBC | Yada, Yada, Yada......5 blasts
Acute myelocytic leukemia
73
42 WBC | Yada, Yada, Yada,....5 L-blasts
Acute lymphocytic leukemia
74
Presence of what cells equals Hodgkin's Lymphoma?
Reed Sternberg cells (via lymph nodes biopsy)
75
Malignant proliferation of what cells is multiple myeloma?
Plasma cells