CB5 Flashcards

1
Q

Health

A

The World Health Organisation define health as ‘a state of complete physical, social and mental well-being, not just simply the absence of disease’

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2
Q

Physical well-being

A

Physical well-being includes being free from disease, eating and sleeping well,getting regular exercise and limiting the intake of harmful substances as drugs and alcohol.

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3
Q

Social well-being

A

Social well-being includes how well you interact with other people and how your surroundings affect you

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4
Q

Mental well-being

A

Mental well-being includes how you feel about yourself

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5
Q

Disease

A

A problem with a structure or process in the body that is not caused by injury

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6
Q

Communicable disease

A

Can be passed from person to person. Caused by a microorganism/pathogen getting in to the body

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7
Q

Non-communicable disease

A

Cannot be passed on from person to person. Caused by a problem in the body such as a fault in the genes or lifestyle choices.

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8
Q

Types of communicable diseases:

A
  • Cholera
  • Ebola
  • Malaria
  • TB
  • HIV
  • Chalara dieback
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9
Q

Types of non-communicable diseases:

A
  • Type 2 diabetes
  • Anaemia
  • Rickets
  • Scurvy
  • Liver cirrhosis
  • Cardiovascular disease
  • Kwashiorkor
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10
Q

A BMI over…

A

A BMI over 30 indicates that someone is obese and at risk of cardiovascular disease

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11
Q

Lifestyle changes

A

Doctors might advise a patient to stop smoking or take up exercise to reduce blood pressure to reduce the risk of cardiovascular disease

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12
Q

Lifestyle changes

Advantage and disadvantage

A

Advantage: Doesn’t need drugs or surgery (free and lacks danger)

Disadvantage: Can be difficult for people to loose weight or give up smoking

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13
Q

Lifelong medication

A

Doctors may give patients with very high blood pressure medicines e.g. beta-blockers to reduce blood pressure and the risk of heart attacks

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14
Q

Lifelong medication

Advantages and disadvantages

A

Advantage: Simple and effective treatment, no risk of surgery

Disadvantage: Drugs can have side effects; people can forget to take them

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15
Q

Surgery

A

Some people have a ‘stent’ put in their blood vessels in a surgery to widen the vessel. People who have these surgeries have to take medicine for the rest of their lives to prevent heart attacks.

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16
Q

Surgery

Advantages and disadvantages

A

Advantage: Effective treatment - makes clots much less likely

Disadvantage: Surgeries are dangerous, especially if people are overweight

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17
Q
Cholera
Type of pathogen
Symptoms of disease
How pathogen is spread
How spread can be reduced/prevented
A
  • Type of pathogen: Bacteria
  • Symptoms of disease: Diarrhoea
  • How pathogen is spread: Drinking infected water
  • How spread can be reduced/prevented: Treating drinking water to kill bacteria. Good hygiene
18
Q
Tuberculosis 
Type of pathogen
Symptoms of disease
How pathogen is spread
How spread can be reduced/prevented
A
  • Type of pathogen: Bacteria
  • Symptoms of disease: Lung damage
  • How pathogen is spread: airborne - inhaling infected sneezes/coughs
  • How spread can be reduced/prevented: cover mouth when coughing/sneezing. TB vaccinations
19
Q
Stomach ulcers 
Type of pathogen
Symptoms of disease
How pathogen is spread
How spread can be reduced/prevented
A
  • Type of pathogen: Helicobacter (bacteria)
  • Symptoms of disease: Stomach pain
  • How pathogen is spread: Oral - touching people’s food after touching own infected mouth
  • How spread can be reduced/prevented: Washing hands before preparing food
20
Q
Malaria
Type of pathogen
Symptoms of disease
How pathogen is spread
How spread can be reduced/prevented
A
  • Type of pathogen: Protist
  • Symptoms of disease: Damage blood and liver causing fever and sickness
  • How pathogen is spread: Animal vectors - mosquitos carry protist from person to person
  • How spread can be reduced/prevented: use mosquito nets to stop them biting
21
Q
Chalara ash dieback
Type of pathogen
Symptoms of disease
How pathogen is spread
How spread can be reduced/prevented
A
  • Type of pathogen: Fungi
  • Symptoms of disease: Leaf loss and bark lessons (damage) in ash trees
  • How pathogen is spread: Airborne - spores in the air carried by wind
  • How spread can be reduced/prevented: Cutting down infected trees
22
Q
Ebola
Type of pathogen
Symptoms of disease
How pathogen is spread
How spread can be reduced/prevented
A
  • Type of pathogen: Virus
  • Symptoms of disease: Haemorrhagic fever (internal bleeding and fever)
  • How pathogen is spread: bodily fluids of infected people getting in to blood of non infected person
  • How spread can be reduced/prevented: Wear gloves and face masks when working with infected people
23
Q
HIV
Type of pathogen
Symptoms of disease
How pathogen is spread
How spread can be reduced/prevented
A
  • Type of pathogen: Virus
  • Symptoms of disease: Destroys white blood cells - causing the onset of AIDS. This means you will get very ill very easily from other pathogens
  • How pathogen is spread: Sexually transmitted infection (STI) contact with sexual fluids
  • How spread can be reduced/prevented: Using a condom, not sharing needles, taking drugs to stop infection spreading from mother to baby
24
Q
Chlamydia
Type of pathogen
Symptoms of disease
How pathogen is spread
How spread can be reduced/prevented
A
  • Type of pathogen: Bacteria
  • Symptoms of disease: Often no obvious symptoms but can lead to infertility
  • How pathogen is spread: Sexually transmitted infection (STI) contact with sexual fluids
  • How spread can be reduced/prevented: using a condom, antibiotics get rid of infection
25
How can our body’s physical and chemical defences protect us from pathogens? Physical:
* Skin - blocks pathogens from getting in to blood * Mucus - traps pathogens and dust in the airways * Cilia - ciliates epithelial cells in the airways have cilia on them. These waft to and fro to move the mucus from the lungs to the throat
26
How can our body’s physical and chemical defences protect us from pathogens? Chemical:
* Hydrochloric acid - produced by the stomach. Kills pathogens on food * Lysozyme - enzymes found in saliva and tears. Breaks down the cell walls of some bacteria to kill them
27
The immune response | Paragraph 1
Pathogens invade the body. Every pathogen has its own specific shaped proteins called antigens on their surface.
28
The immune response | Paragraph 2
The antigens tell the body that the pathogen is ‘foreign’ and shouldn’t be there - this triggers the immune response. This activates white blood cells called lymphocytes which have antibodies that match the antigens
29
The immune response | Paragraph 3
In the immune response, the lymphocytes produce and release lots of antibodies which match the shape of the antigens
30
The immune response | Paragraph 4
The antibodies bind to the antigens on the pathogen and destroy the pathogen
31
The immune response: describe and explain the graph | Paragraph 1
At the first injection, a smaller number of antibodies are produced over a long period of time. There is a lag one of a few days after infection with the pathogen before any antibodies are produced at all
32
The immune response: describe and explain the graph | Paragraph 2
A second infection causes a secondary response. Memory lymphocytes male more antibodies, more quickly. The pathogens are killed quickly so you don’t get ill - you are immune to the pathogen
33
Vaccines | Point 1
• Vaccines inject an inactive version of the pathogen and its antigens in to you. The body fights this like a real infection
34
Vaccines | Point 2
• Memory lymphocytes are made in response to the vaccine and stay in the blood so if you are ever infected by the pathogen they make a lot of antibodies very quickly and you don’t get ill
35
Vaccines | Point 3
• You are immune
36
Antibiotics
* Antibiotics can only be used to treat bacterial infections | * They inhibit (stop) cell processes e.g. mitosis
37
Developing new medicines | Stage 1
Discovery - finding a new drug which might cure/treat a disease
38
Developing new medicines | Stage 2
Preclinical - testing the drug on cells in the lab to see if it enters the cells and has the effect we want
39
Developing new medicines | Stage 3
Animal testing - testing the drug on animals is to check it works on a whole organism but without causing harm to humans
40
Developing new medicines | Stage 4
Small clinical trial - test on a small number of people to check the drug is safe and does not have bad side effects
41
Developing new medicines | Stage 5
Large clinical trial - test on a large number of people with the disease to find out the correct dose and check for side effects