Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

neuropharm > CATECHOLAMINES > Flashcards

CATECHOLAMINES Flashcards

1
Q

AMPT

A

blocks TH, decreases synthesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

VMATs purpose

A

load catecholamines into synaptic vesicles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

VMATs blocked

A

by resperine, used for Huntington’s

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Single spiking mode

A

action potentials at irregular intervals (tonic)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Burst mode

A

2-20 spikes at higher frequency (phasic)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

MAO and COMT

A

catecholamine breakdown, produce metabolites

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

nonselective MAO inhibitors

A

used to treat depression but with dangerous side effects

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

HVA

A

DA metabolite

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

MHPG and VMA

A

NE metabolite

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

DA cell groups location

A

substantia nigra and VTA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

dopamine deficient mouse

A

hypoactive

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

D1

A

stimulate adenylyl cyclase and increase cAMP synthesis (metabotropic)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

D2

A

inhibit cAMP synthesis and regulate ion channels for K

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

DA receptor antagonist

A

suppress locomotor behavior

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

D2 antagonist

A

cause behavioral supersensitivity due to up regulation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

DA transporter knockout animals

A

hyperactive

17
Q

NE location

A

pons and medulla and LC

18
Q

blood borne NE

A

sympathetic, fight or flight

19
Q

adrenoreceptors

A

metabotropic

20
Q

B1 and B2 receptors

A

stimulate adenylyl cyclase and enhance formation of cAMP

21
Q

a2 receptors

A

inhibit adenylyl cyclase and reduce cAMP

22
Q

a2 agonist

A

inhibit noradrenergic cell firing

23
Q

a2 antagonist

A

blocks autoreceptors

24
Q

passive avoidance learning

A

increase EPI and NE

25
Q

Catecholamines synthesis

A

from tyrosine

26
Q

rate limiting enzyme

A

tyrosine hydroxylase

27
Q

B2 adrenoceptor agonist used for

A

COPD and asthma

28
Q

a1 receptor agonist

A

phenylephrine, decongestant

neuropharm (5 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions