ACETYLCHOLINE Flashcards

1
Q

Ach synthesized by

A

choline and acetyl CoA

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2
Q

Ach catalyzed by

A

ChAT

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3
Q

Ach loaded into vesicles by

A

VACHT

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4
Q

vesamicol

A

blocks VACHT

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5
Q

botulism

A

prevents fusion of synaptic vesicles with terminal membrane

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6
Q

Ach broken down by

A

AchE

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7
Q

Ach broken down to

A

choline and acetic acid

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8
Q

forms of AchE

A

soluble, G4 tethered, A12

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9
Q

AchE reversible inhibitors treat

A

dementia, glaucoma

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10
Q

irreversible AchE inhibitors

A

organophosphorus compounds

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11
Q

LDTg and PPTg roles

A

drug reward and reinforcement and REM

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12
Q

nicotinic receptors

A

inotropic,

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13
Q

muscarinic receptors

A

metabotropic, used to treat psych disorders, cause dry mouth

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