Catabolic Pathways

Question 1

A series of 10 enzyme-catalyzed reactions by which glucose is oxidized to two molecules of pyruvate

Answer 1

Glycolysis

Question 2

Phosphorylation of a-D-glucose

Answer 2

[glycolysis] Reaction 1

Question 3

Isomerization of a-D-glucose 6-phosphate to a-D-fructose 6-phosphate

Answer 3

[glycolysis] Reaction 2

Question 4

this isomerization is most easily seen by
considering the open-chain forms of each monosaccharide. It is one keto-enol tautomerism followed by another

Answer 4

[glycolysis] Reaction 2

Question 5

Phosphorylation of fructose 6-phosphate

Answer 5

[glycolysis] Reaction 3

Question 6

Cleavage of fructose 1,6-bisphosphate to two triose phosphates

Answer 6

[glycolysis] Reaction 4

Question 7

Isomerization of triose phosphates

Answer 7

[glycolysis] Reaction 5

Question 8

Oxidation of the –CHO group of D-glyceraldehyde 3-phosphate

Answer 8

[glycolysis] Reaction 6

Question 9

Transfer of a phosphate group from 1,3-bisphosphoglycerate to ADP

Answer 9

[glycolysis] Reaction 7

Question 9

Isomerization of 3-phosphoglycerate to
2-phosphoglycerate

Answer 9

[glycolysis] Reaction 8

Question 10

Dehydration of 2-phosphoglycerate

Answer 10

[glycolysis] Reaction 9

Question 10

Phosphate transfer to ADP and formation of ATP

Answer 10

[glycolysis] Reaction 10

Question 11

most commonly metabolized

Answer 11

Pyruvate

Question 12

in the conversion of Pyruvate to Acetyl-CoA under aerobic conditions, pyruvate undergoes __________

Answer 12

oxidative decarboxylation

Question 12

Simplified schematic representation of the pentose phosphate pathway, also called

Answer 12

shunt

Question 12

T or F: Glycerol enters glycolysis via dihydroxyacetone phosphate

Answer 12

True

Question 13

A series of four enzyme-catalyzed reactions that cleaves carbon atoms two at a time from the carboxyl end of an acyl CoA

Answer 13

B-Oxidation

Question 14

Oxidation by FAD of the , carbon-carbon single bond to a carbon-carbon double bond

Answer 14

[β-Oxidation] Reaction 1

Question 15

Hydration of the C=C double bond to give a 2°
alcohol

Answer 15

[β-Oxidation] Reaction 2

Question 16

Oxidation of the 2°alcohol to a ketone

Answer 16

[β-Oxidation] Reaction 3

Question 17

Cleavage of the carbon chain by a molecule of CoA-SH

Answer 17

[β-Oxidation] Reaction 3

Question 17

Are formed principally in liver mitochondria and can be used as a fuel in most tissues and organs

Answer 17

Ketone Bodies

Question 17

T or F: Formation occurs when the amount of acetyl CoA produced is less compared to the amount of oxaloacetate available to react with it and take it into the TCA

Answer 17

False - acetyl coa produced is excessive

Question 18

–NH2 groups move freely by _________

Answer 18

transamination

Question 19

a cyclic pathway that produces urea from CO2 and NH4+

Answer 19

Urea Cycle