CASE PRESENTATION STUDY Flashcards
What is hypertension?
High blood pressure
What are some known risk factors for development of hypertension?
- age (older)
- obesity
- family history
- tobacco
- poor diet
- alcohol
- genetics
How is hypertension graded?
Graded using the NICE definition
- Stage 1 (mild)
- Stage 2 (moderate)
- Stage 3 (severe)
What are the measurements that classify “mild” hypertension?
Systolic = 140-159mmHg
Diastolic = 90-99mmHg
What are the measurements that classify “moderate” hypertension?
Systolic = 160-179mmHg
Diastolic = 100-109mmHg
What are the measurements that classify “severe” hypertension?
Systolic = 180mmHg or higher
Diastolic = 110mmHg or higher
What readings would be considered hypertensive crisis?
Systolic = 180mmHg+
Diastolic = 120mmHg+
How severe is your patients hypertension?
Mild according to pt
What are the symptoms of hypertension?
- Often none
- Headache (especially in the morning)
- Nosebleeds
- Blurred vision
- Shortness of breath
What medications can be used to treat hypertension?
- beta blockers
- ACE inhibitors
- diuretics
- calcium channel blockers
- ARB (angiotensin II receptor blocker)
What type of drug is Candesartan?
Angiotensin II receptor blocker
How does Candesartan work?
- Blocks angiotensin II type 1 receptors (located on blood vessels)
- blocks the effects of Angiotensin II such as vasoconstriction and aldosterone secretion (hormone that promotes salt & water retention)
- Both of these lead to reduced blood pressure
What are potential side effects of Candesartan?
- Dizziness and lightheaded
- Postural hypotension
- Fatigue
- Nausea
- Diarrhoea
Why is cataract surgery indicated?
Clouding of the eye causing visual impairment. Occurs due to:
- aging
- genetics
- trauma
- medical conditions (eg diabetes)
- long term use of corticosteroids
What is a detached retina?
the retina (light sensitive layer of tissue at back of eye) becomes separated from underlying connective tissues
- leads to severe visual impairment
How might a detached retina affect his dental history?
Poor central vision in right eye =
- difficulty with OH
- progressive loss of vision
What is the mechanism of action of statins?
Used to lower cholesterol levels in the body
- inhibits the HMG-CoA reductase enzyme
- this enzyme plays a crucial role in the synthesis pathway of cholesterol in the liver
- therefor a reduction in liver production of cholesterol
- liver increases expression of LDL receptors, so LDL cholesterol is cleared from bloodstream quicker
What are the clinical benefits associated with statins?
reduction in production of atherosclerotic plaques therefor reduced CV risk
Common statins:
- atorvastatin
- simvastatin
Side effects of statins:
- liver function changes
- increased blood sugar [risk of developing type 2 diabetes] in some individuals
- drug interactions
Statin effects on dental tx?
- Liver function changes so be careful when using LA metabolised in liver if this is the case (eg Lidocaine)
- Xerostomia leading to higher caries risk
- Interactions with Azole antifungals so need to be careful
What medications do statins interfere with?
- “Azole” antifungals
- Clarithromycin
- Phenytoin
- Warfarin (mess up the INR level)
How can cadasartan interfere with dental tx?
- Orthostatic/postural hypotension due to low BP
- Xerostomia
- Interaction with NSAIDs [they reduce the effect of Candesartan]
What allergy does your patient suffer from?
Allergy to ibuprofen
Discuss ibuprofen allergy:
Drug hypersensitivity reaction
What are symptoms of ibuprofen allergy?
- Skin reactions = hives, itching, redness
- Respiratory = shortness of breath, wheezing coughing
- Angioedema = lip/face/throat swelling
- GI = vomiting, nausea, diarrhoea, abdominal pain
How might an ibuprofen allergy be diagnosed?
- Skin testing/patch testing
- Drug challenge test
What type of hypersensitivity reaction is an ibuprofen allergy?
Can be:
- Type I (immediate hypersensitivity) *** most common
- Type III (immune complex)
- Type IV (delayed hypersensitivity)
What is the mechanism of Type I hypersensitivity reaction?
- mediated by immunoglobin IgE antibodies
- when exposed to the allergen (ibuprofen), IgE binds to mast cells and basophils
- leads to the release of histamine and inflammatory products
What are the clinical presentations of a Type I hypersensitivity reaction?
- hives
- angioedema
- respiratory symptoms
- anaphylaxis
What is anaphylaxis?
severe and life-threatening allergy condition
How many sugar intakes per day makes someone high caries risk?
3+ sugar intakes per day at separate times
What effect does smoking have on general health?
Smoking can lead to:
- respiratory diseases (COPD, cancer)
- CV disease (atherosclerosis, stroke, heart attack)
- cancer (lung, throat, oral, stomach)
- reduced immune function
- lowered reproductive health
What effect does smoking have on oral health?
Increased risk of
- Periodontal disease
- Oral cancer
- Delayed healing
- Halitosis and tooth staining
- Chronic hyperplastic candidosis
-
How does smoking increase periodontal disease risk?
- Vasoconstriction of gingival tissues (reduction in oxygen & nutrients to gingiva)
- Impaired chemotaxis of neutrophils/macrophages to fight off periodontal causing bacteria
- Increased osteoclast activity leading to bone resorption
- Impaired wound healing & collagen production
What bacteria are involved in periodontal disease?
- P. gingivalis
- Prevotella intermedia
How much more likely are you to develop oral cancer if you smoke? (no alc)
2x more likely (increases with frequency and consumption)
How much more likely are you to develop oral cancer if you drink alcohol?
2x more likely
How much more likely are you to develop oral cancer if you smoke AND drink alcohol?
5x more likely (synergistic effect)
Risk factors for oral cancer development?
- Smoking
- Alcohol
- HPV infection
- UV
- Stress
- Age (60+)
- Gender (male)
What is the significance of pack years?
Higher pack year value = increased risk of developing negative effects associated with smoking
Explain the synergistic effect of smoking and alcohol consumption on development of oral squamous cell carcinoma:
- Alcohol compromises the mucosal barrier, allowing easier passage of smoking carcinogens into the body
- Both impair the immune system
- Increased risk of OSCC development
What is the recommended max limit of alcohol intake per week?
14 units per week, spread over 3 days with at least 2 alc free days
How many units in a pint of beer? (approx)
2 units
How many units in a pint of guinness?
2.4 units
What is geographical tongue?
Benign condition that causes patchy atrophic areas on the tongue “map like pattern”
What are the causes of geographical tongue?
- Genetics
- Idiopathic
- Zinc deficiency
- Hormonal fluctuations (eg pregnancy)
- Associated with other autoimmune/inflammatory conditions eg psoriasis
Symptoms of geographical tongue?
- Often none
- Burning/stinging sensation when eating acidic or spicy foods
What is the clinical presentation of geographical tongue?
- smooth, irregularly shaped red patches on the tongue with white margins
- migratory nature (tends to change a lot)
- lack of filiform papillae in affected area
What does TTP suggest?
- periapical involvement/infection/periodontitis
- pulpitis
- cracked tooth syndrome
- occlusal trauma
What is the purpose of a BPE?
Screening tool for periodontal disease detection, does not DIAGNOSE
What does sensibility testing involve?
- Ethyl Chloride
- EPT
What does 6PPC record?
- Gingival level
- Pocket depth
- LOA
- Mobility
- BoP
- Furcation
What is meant by loss of attachment?
Loss of attachment is the distance from the CEJ, to the base of the periodontal pocket
- indicates the cumulative loss of supporting periodontal tissues, including gum, periodontal ligament, and alveolar bone.
What dosage is a PA radiograph?
4uSv
What dosage is an OPT radiograph?
20uSv
What is condensing osteitis?
localised area of increased bone density associated with chronic low grade inflammatory stimulus (lack of PA radiolucency)
Causes of condensing osteitis:
- chronic pulpal inflammation
- non-vital teeth
What is attrition?
The physiological wearing away of tooth structure as a result of tooth to tooth contact
What is erosion?
The loss of tooth tissue as a result of a chemical process that does not involve bacteria
What types of toothwear exist?
- Erosion
- Attrition
- Abfraction
- Abrasion
What is meant by generalised periodontitis?
> 30% of teeth are affected
What is meant by stage III periodontitis?
Bone loss extending to the mid-third of the root
What is meant by grade B periodontitis?
Rate of progression number is between 0.5-1.0 (moderate rate of progression)
What is meant by “currently unstable” in a periodontal diagnosis?
BoP (inflammation is currently present)
Aside from smoking, what other risk factors play a role in periodontal disease?
- Diabetes
- Pregnancy
- Stress
Why are defective bridge and crown margins a problem?
- Marginal leakage leading to secondary caries
- Periodontal problems (irritation to surrounding gingiva)
- Poor retention & stability
- Poor aesthetics
- Difficult to keep clean
- Compromised RCT coronal seal
Ideal post dimensions?
- Parellel
- Non-threaded
- Cement retained
Why is a parallel post preferred?
- uniform stress distribution
- improved retention
Why is a non-threaded post preferred?
- no rotational “screw” stress factors created on placement
- easier removal upon retreatment
Why is a cement retained post preferred?
- more reliable retention
- helps distribute occlusal forces down long axis of tooth
Are this patients post-restorations ideal?
FAR FROM IT
- 13 = inadequate obturation, post is threaded
- 11 = inadequate obturation, too short from apex
Explain the pulp nerves of a tooth with irreversible pulpitis:
A-delta fibres = myelinated fibres that are stimulated via acute stimuli, cause sharp pain
C fibres = unmyelinated fibres located deeper in the pulp that are stimulated by more aggressive or chronic stimuli, cause dull aching pain
Inflammation of pulpal tissues causes pressure to build up which causes pain
What is involved in step one of periodontal treatment based on BSP 2017 guidelines?
- Explain periodontal disease, risks/benefits of tx
- OHI
- Control risk factors (eg removal of plaque retentive factors, smoking cessation, diabetes control)
- Supra and some subgingival PMPR
What is involved in step two of periodontal treatment based on BSP 2017 guidelines?
- Subgingival PMPR
- Further control of risk factors
- Use of adjunctive antimicrobials
What is involved in step three of periodontal treatment based on BSP 2017 guidelines?
- Reinforce OH, behaviour change, risk factors
- Subgingival PMPR on moderate residual pockets (4-5mm)
- Consider surgery for pockets >6mm
What type of periodontal surgery exists?
- Flap raising surgery
- Regenerative surgery
- ## Root resection
What are the different mobility scores & their meaning?
1 = <1mm movement
2 = 1-2mm movement
3 = >2mm movement and/or rotation/vertical movement
What are the different furcation scores & their meaning?
1 = less than 1/3
2 = >1/3
3 = through and through lesion
Why are cuspal coverage restorations better?
- Better load distribution down long axis of tooth because cusps are covered
- Prevents crack propagation which can be a problem in direct restorations
- Stronger materials eg Zirconia
- Precision fabrication in laboratory so usually perfect fit to crown of tooth
Why did you decide to use composite for these restorations>
- Composite is aesthetic
- Bonds directly to tooth surface
- Patient preference
- Moisture control could be easily achieved
- Minimally invasive, less tooth tissue destruction
Explain the steps of caries removal:
- Locate and identify carious enamel and remove to the extent of the ADJ
- Remove peripherally at the ADJ until margins are clear
- Then remove caries circumferentially
- Remove deep caries with a slow speed or excavator
What type of bridge does your patient have?
Fixed-fixed conventional design
What is a metal ceramic crown?
Consists of:
- metal substructure
- opaceous ceramic layer
- veneering ceramic layer
What are the advantages of MCCs?
- Stronger than conventional all ceramic crowns
- Reasonable aesthetics
What are the disadvantages of MCCs?
- More extensive tooth prep
- Cost
- Can get metal shine-through
Anterior MCC prep values?
- Incisal reduction 2mm
- Labial prep 1.5mm
- Palatal prep 0.5mm-1mm chamfer
What luting agent would be used to cement a MCC?
GIC = Aquacem
RMGIC = RelyX
What type of pontic does this patient have?
Ridge lap pontic
What is SDA?
Loss of most posterior teeth but maintained function and occlusal stability with remaining anterior dentition (requires 3-5 occlusal units minimum)
Is this patient suitable for SDA?
Not really due to periodontal involvement and poor prognosis of remaining dentition however pt does not want an RPD so nothing we can do
How are posts removed from teeth?
- Ultrasonics
- Sliding hammer
- Masseran
- Heat application to soften cement
What risks are associated with leaving a tooth in the mouth with a chronic draining sinus?
Risk of:
- spread of infection
- sepsis risk if infection worsens
- stress on the immune system
- flare ups of swelling and pain
- subsequent tooth loss eventually
What are the advantages of creating an immediate denture?
- Restores aesthetics
- May help speech
- Function
- Avoids drifting/tilting/over-eruption of remaining teeth
- Prevents collapse of facial musculature
What are the disadvantages of an immediate denture?
- Temporary fit
- Poor adaptation to ridge due to post-extraction resorption
- If pt excessively swells, denture wont fit
What instructions do you give to pt after delivery of immediate denture?
Leave in for first 24 hours.
Reviews at:
- 1/2 days
- 1/2 weeks
- 1 month
How does caries occur in relation to Stephan curve?
- Fermentable carbohydrates/sugar consumed
- Strep Mutans metabolises it and creates lactic acid
- pH drops below critical threshold 5.5
- demineralisation occurs
- caries formation favourable
- saliva buffers and brings pH back up to 6.5/7
What type of luting cement might you use to cement a zirconia crown?
GIC
- Aquacem