Cartilage and Collagen Flashcards

1
Q

Name 4 types of cartilage?

A
  1. Fibrocartilage
  2. Articular (hyaline) cartilage
  3. Elastic cartilage (trachea)
  4. Epiphyseal cartilage
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2
Q

Key transcription factor for cartilage differentiation?

A

SOX-9

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3
Q

Fibrocartilage cartilage type and example?

A

1

Tendon/ligament junction with bone

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4
Q

Healing response to articular cartilage damage?

A

Fibrocartilage

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5
Q

Elastic cartilage main collagen and example?

A

Type 2 collagen

Ear

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6
Q

Zones of epiphyseal cartilage?

A
  1. Resting zone
  2. Proliferating zone
  3. Hypertrophic zone
  4. Spongiosum
  5. Groove of ranvier
  6. La croix
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7
Q

Type 3 collagen found in? 2

A

Skin and blood vessels

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8
Q

Function of type XI collagen?

A

Superglue - holds the collagen lattice together in cartilage

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9
Q

Type X collagen produced by?

A

Hypertrophic chondrocytes during enchondral ossification

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10
Q

Type X collagen function?

A

Ossification of the cartilage

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11
Q

Type V, VI, IX Collagen occur in small amounts where>

A

Articular cartilage

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12
Q

2 alpha 1 and 1 alpha 2 chains of collagen combine to form?

A

Procollagen

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13
Q

Procollagen is processed and expressed from Golgi apparatus as?

A

Tropocollagen

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14
Q

Multiple collagen fibrils combine to form?

A

Collagen fibre

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