Cartilage and Collagen Flashcards
Name 4 types of cartilage?
- Fibrocartilage
- Articular (hyaline) cartilage
- Elastic cartilage (trachea)
- Epiphyseal cartilage
Key transcription factor for cartilage differentiation?
SOX-9
Fibrocartilage cartilage type and example?
1
Tendon/ligament junction with bone
Healing response to articular cartilage damage?
Fibrocartilage
Elastic cartilage main collagen and example?
Type 2 collagen
Ear
Zones of epiphyseal cartilage?
- Resting zone
- Proliferating zone
- Hypertrophic zone
- Spongiosum
- Groove of ranvier
- La croix
Type 3 collagen found in? 2
Skin and blood vessels
Function of type XI collagen?
Superglue - holds the collagen lattice together in cartilage
Type X collagen produced by?
Hypertrophic chondrocytes during enchondral ossification
Type X collagen function?
Ossification of the cartilage
Type V, VI, IX Collagen occur in small amounts where>
Articular cartilage
2 alpha 1 and 1 alpha 2 chains of collagen combine to form?
Procollagen
Procollagen is processed and expressed from Golgi apparatus as?
Tropocollagen
Multiple collagen fibrils combine to form?
Collagen fibre