Cartilage and bone Flashcards

1
Q

what fetal cells does cartilage and bone differentiate

A

mesenchyme cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what are the three cells active in the matrix

A

fibroblast
chondroblast
osteoblast

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what are the three resting cells

A

fibrocyte
chondrocyte
osteocyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

where do resting cells reside

A

lacunae

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what do fibroblasts do

A

produce collagen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what do chondroblasts do

A

produce cartilage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what do osteoblasts do

A

produce bone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what do osteoclasts do

A

breakdown bown

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what is cartilage

A

firm extracellular chondrin matrix
sulphated mucopolysaccharide gel intermeshed with type II collagen fibres

no nerves, rarely any blood vessels
often surrounded by the perichondrium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what does the fibres and gel resist

A

fibres resist tension
gel resist compression

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what is collagen laid down by

A

chondroblasts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what are the four types of cartilage

A

Hyaline skeletal
elastic skeletal
fibrocartilage
articular cartilage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

hyaline skeletal

A

simplest, may mineralise in old age
found upper respiratory tract, ventral ribs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

elastic skeletal

A

contains elastin fibres
found external ear, upper respiratory tract

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Fibrocartilage

A

alternating layers of hyaline cartilage and collagen
found: intervertebral discs, symphyses, scuta, labra, menisci, discs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Articular cartilage

A

complex, partly fibrous, partly hyaline form

17
Q

what is the precursor of bone development

A

hyaline skeletal

18
Q

Functions of bone

A

compression/resistive structures - struts, levers
protection (cranium protecting brain, ribs protecting lungs/heart)
Elastic potential energy store
Acoustic (middle ear ossicles)
Display or combat (antlers)
Blood cell production in bone marrow
mineral store

19
Q

what is the matrix (osteoid) composed off

A

one third by weight type I collagen
two thirds by weight hydroxyapatite with absorbed calcium carbonate (3 salts of calcium)

20
Q

What do osteoblasts do

A

make bone
may live as long as the animal

21
Q

What do osteoclasts do

A

break bone
myeloid blood cell derived
multinucleated
large cells (lots stuck together)
short lived

22
Q

how is bone formation/destruction controlled

A

hormonally
by parathyroid hormone, calcitonin, Vitamin D

23
Q

Classification of bones by location

A

axial and appendicular
cranial and postcranial

24
Q

Classification of bones by morphology (shape)

A

long (humerus)
short (carpals)
Flat (scapula, skull)
irregular (vertebrae, skull)
sesamoids (patella, in tendons)