Cartilage Flashcards
Function of Hyaline cartilage
Supports and reinforces
Resist compressive stress
Structures of hyaline
Condroblast produce the matrix
Chondrocyte are matured condroblast
Chrondrocyte lie in lacunae
Location of hyaline
Larynx,trachea, cartilage of nose,ribs and intercostal muscles
Location of elastic cartilage
Epiglottis and pinna
Structure of elastic
Similar to hyaline(except fibers)
Elastic have more elastic fibers
Function of elastic fibers
Maintains the shape of a structure
Allows great flexibility
Structure of fibrocartilage
Thick collagen fibers
Firm matrix but similar to hyaline cartilage
Collagen fibres are parallel
Condrocyte between collagen fibres
Function of fibrocartilage?
Tensile strength
Absorb compressive shock
Location of fibrocartilage
Intervertebral discs
Knee joint
Function of cartilage
Tiisues bear Mechanical stresses Shock absorbing without permanent distortion Supports soft tissues Smooth surface allows Sliding against it Growth and development of bone
What does Ground substance contains?
It contains of proteoglycans
What does proteoglycans consists of
Sulphated and Non-sulphated GAGs
Where does Hyaluronic acid arise from?
Non-sulphated GAGs
What does sulphated GAGs consist of
Chondroitin and keratan Sulphate
What nourishes chrondrocytes and houses blood vessels?
Perichondrium
What plays a role in growth and repair of Cartilage?
Perichondrium
Which type of collagen does perichondrium have?
Type 1 collagen
What are rounded cartilage precursor cells formed from differentiation of mesenchymal Cells?
Chondroblast
Which type of collage does hyaline cartilage Have?
Type II
Which cartilage serves as as temporary selection in embryo?
Hyaline cartilage
Articular cartilage is differentiated into which four zones?
Superfacial zone
Middle/transitional zone
Deep/transitional zone
Calcified zone
Superfacial zone?
First zone
Smooth region
Provides sliding surface
Middle zone?
2nd zone
Increases tensile strength
Compression resistance
Deep zone?
3rd zone
It has highest proteoglycans surface
Provides greatest resistance
Calcified zone?
Last zone
Lowest level of cartilage
Type of cartilage fibrocartilage has?
Type 1 and oriented parallels to stress plane
Where can we find isogenic group?
In hyaline and fibrocartilage only
Two types of cartilage growth?
Interstitial growth-middle
Appositional -at the edge
Describe interstitial growth
- mitotic division of pre-existing Chondrocyte
- Synthesis of matrix
- Expands cartilage matrix within
- Occurs in epiphyseal plates
Describe Appositional growth?
Differentiation of pericondrial cells into condroblasts
Synthesis of matrix
Increase in girth
