Cartilage Flashcards

1
Q

Function of Hyaline cartilage

A

Supports and reinforces

Resist compressive stress

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2
Q

Structures of hyaline

A

Condroblast produce the matrix
Chondrocyte are matured condroblast
Chrondrocyte lie in lacunae

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3
Q

Location of hyaline

A

Larynx,trachea, cartilage of nose,ribs and intercostal muscles

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4
Q

Location of elastic cartilage

A

Epiglottis and pinna

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5
Q

Structure of elastic

A

Similar to hyaline(except fibers)

Elastic have more elastic fibers

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6
Q

Function of elastic fibers

A

Maintains the shape of a structure

Allows great flexibility

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7
Q

Structure of fibrocartilage

A

Thick collagen fibers
Firm matrix but similar to hyaline cartilage
Collagen fibres are parallel
Condrocyte between collagen fibres

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8
Q

Function of fibrocartilage?

A

Tensile strength

Absorb compressive shock

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9
Q

Location of fibrocartilage

A

Intervertebral discs

Knee joint

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10
Q

Function of cartilage

A
Tiisues bear Mechanical stresses 
Shock absorbing without permanent distortion 
Supports soft tissues 
Smooth surface allows Sliding against it
Growth and development of bone
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11
Q

What does Ground substance contains?

A

It contains of proteoglycans

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12
Q

What does proteoglycans consists of

A

Sulphated and Non-sulphated GAGs

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13
Q

Where does Hyaluronic acid arise from?

A

Non-sulphated GAGs

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14
Q

What does sulphated GAGs consist of

A

Chondroitin and keratan Sulphate

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15
Q

What nourishes chrondrocytes and houses blood vessels?

A

Perichondrium

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16
Q

What plays a role in growth and repair of Cartilage?

A

Perichondrium

17
Q

Which type of collagen does perichondrium have?

A

Type 1 collagen

18
Q

What are rounded cartilage precursor cells formed from differentiation of mesenchymal Cells?

A

Chondroblast

19
Q

Which type of collage does hyaline cartilage Have?

A

Type II

20
Q

Which cartilage serves as as temporary selection in embryo?

A

Hyaline cartilage

21
Q

Articular cartilage is differentiated into which four zones?

A

Superfacial zone
Middle/transitional zone
Deep/transitional zone
Calcified zone

22
Q

Superfacial zone?

A

First zone
Smooth region
Provides sliding surface

23
Q

Middle zone?

A

2nd zone
Increases tensile strength
Compression resistance

24
Q

Deep zone?

A

3rd zone
It has highest proteoglycans surface
Provides greatest resistance

25
Q

Calcified zone?

A

Last zone

Lowest level of cartilage

26
Q

Type of cartilage fibrocartilage has?

A

Type 1 and oriented parallels to stress plane

27
Q

Where can we find isogenic group?

A

In hyaline and fibrocartilage only

28
Q

Two types of cartilage growth?

A

Interstitial growth-middle

Appositional -at the edge

29
Q

Describe interstitial growth

A
  1. mitotic division of pre-existing Chondrocyte
  2. Synthesis of matrix
  3. Expands cartilage matrix within
  4. Occurs in epiphyseal plates
30
Q

Describe Appositional growth?

A

Differentiation of pericondrial cells into condroblasts
Synthesis of matrix
Increase in girth