Caries & caries prevention Flashcards
Where does decay begin?
Decay begins inside the tooth and breaks out onto surface.
What are 4 components of biofilm?
S. mutans, S. sobrinus, Lactobacilli, and other pathogens
Describe plaque biofilm formation at 12 hours? 24 hrs? 10 days?
12 hrs: soft, still removable by fingernails
24 hrs: begins to harden
10 days: considered Tartar or Calculus
What is enamel pellicle? What’s good about it? What’s bad?
Enamel pellicle is a layer laid down by bacteria almost immediately after cleaning. It is good because it seals out acids. Bad because it doesn’t allow remineralization and provides a surface that bacteria, especially S. mutans can attach to more easily.
How do S. mutans attach to the pellicle?
Using extracellular polysaccharides (Glucans)
What are the two main ingredients in enamel?
Ca & P
Can cementum and dentin be remineralized?
No
Enamel is the most highly mineralized structure in the human body. What is it composed of? (Non-chemical comp)
Tightly packed carbonated hydroxyapatite crystals. Arranged in rod (cross section) or crystal form.
What structure of enamel allows for fluid diffusion?
The intercrystalline spaces between rods of the carbonated hydroxyapatite crystals allows for fluid diffusion. The intercrystalline space is filled with water and organic material.
How do demineralization zones spread to the enamel?
They follow the rods through the enamel and spread at the DEJ
What teeth fall into high susceptibility (2), intermediate susceptibilty (3), and low susceptibilty (3) zones for carious lesions?
High susceptibility: Mandibular & maxillary molars
Interm Susceptibilty: Maxillary & mandibular premolars; maxillary incisors
Low Susceptibilty: Maxillary canines, mandibular incisors, and mandibular canines
What are the three main salivary glands in the mouth? What is the duct associated with each?
- Parotid gland w/ Stenson’s Duct
- Submandibular gland w/ Wharton’s duct
- Sublingual gland w/ Bartholin’s duct
What are the three non-antimicrobial, beneficial functions of saliva in the mouth?
- Lubrication and flushing of food particles in the mouth
- Dilution and chemical buffering of acid
- Provide calcium and phosphate for buffering
What are the three antimicrobial functions of saliva in the mouth?
- Mucin causes bacterial aggregation
- Lactoferrins inhibit S. mutans adherence and deprive bacteria of iron
- Peroxidase inhibits ability to use glucose
What is the property of many medications that causes xerostomia?
Anticholinergic properties, block the neurotransmitter acetylcholine, causing, among other things, severe dry mouth.
What are three categories of medicine that commonly cause xerostomia? What is an additional aspect of many medications that increases caries risk?
- Anti-anxiety & anti-psychotic medication
- Anti-hypertensive agents (cholesterol lowering drugs)
- Allergy and asthma medication, especially inhaled glucocorticosteroids.
Additionally, many medications include sugar to make them taste better.
3 recommendations for people with dry mouth?
- Artificial saliva
- Increase water
- Xylitol or sugarless gum
Why is radiation, treatment for oral cancer, so detrimental to oral health?
It kills salivary glands and stops production of saliva = severe dry mouth
For how long after eating does the pH in the mouth remain acidic?
20 minutes
What important characteristic relating to food intake and acidity does the Stephan curve show?
The Stephan curve shows that increasing the amount of food or the concentration of sugars in the food does not significantly decrease pH or make the length or time that your mouth is acidic longer. Therefore it’s not necessarily how much you eat but how OFTEN you eat that determines the amount of time your mouth is at a pH below 5.5.
Where is the best place to go for evidence based info on dentistry
CDC website
How does flouride enhance remineralization?
Fluoride attracts first Calcium and then Phosphate ions, speeding up remineralization. Fluoride also EXCLUDES carbonate to allow more fluorapatite crystal growth (fluorapatite crystals are better than hydroxyapatite crystals).
How does fluoride decrease demineralization?
Fluoride, in water phase, fills intercrystalline spaces making it more difficult for acids to enter spaces and dissolve teeth.
Fluorapatite (FAP) in enamel crystal lattice is more resistant to demineralization that hydroxyapatite, therefore, demineralization is inhibited.
How does fluoride inhibit bacterial metabolism?
Fluoride is converted to hydrogen fluoride ions (HF) in the presence of acid. HF is incorporated into cells w/in plaque biofilms. There HF reduce acid by inhibiting enolase, a key enzyme in carbohydrate metabolism, therefore reducing acid production.
- Reduces mucopolysaccharides
- Inhibits glycolysis
Give 2 ways systemic fluoride prevents caries beyond remineralization, bacterial inhibition, etc…
- Affects developing tooth enamel via the bloodstream by increasing fluorapatite crystals in developing teeth
- Excreted in saliva for topical effects
What are the two flourides used in toothpaste (dentifrice)? Which is used more often? What company uses the lesser common fluoride? What is an additional benefit provided by the lesser common fluoride?
- 0.2% Sodium Fl 1000 ppm- most common
2. 0.454% Stannous Fl ppm- Crest Pro Health, also provides antibacterial benefits
What is the age to which children should be supervised while brushing and flossing?
Approximately 8 yrs old. until they can write cursive.
Cochrane systematic review pooled 24 studies on fluoride toothpaste and water fluoridation. What were the findings of the study?
- Found caries reduction of 24% with consistent brushing with fluoridated toothpaste. Especially true for:
- People with higher baseline caries levels
- The higher the fluoride concentration in the toothpaste
- Higher frequency of use
- Parental or teacher supervision of brushing
- Interestingly found that water fluoridation did not have a significant influence on the presence of caries
In a study presented in class assessing effectiveness of fluoride home rinses for children found what?
A 26% reduction in prevalence of decayed, missing, or filled teeth.