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Pharmacy Practice V > Cardiovascular Indication and Dosing > Flashcards

Cardiovascular Indication and Dosing Flashcards

1
Q

What is the dosing of Lopressor for CAD/AFib?

A

BID

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2
Q

What is the dosing of Toprol XL for HFrEF?

A

Start: 12.5 QD
Target: 200 QD

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3
Q

How often do you titrate Toprol XL for HFrEF?

A

Double dose every 2 weeks until you reach the highest tolerated amount

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4
Q

What is the dosing of Zebeta for HFrEF?

A

Start: 1.24 QD
Target: 10 QD

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5
Q

How often do you titrate Zebeta for HFrEF?

A

Double the dose every 2 weeks until you reach the highest tolerated amount

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6
Q

What is the initial dosing of Coreg for HFrEF?

A

Start: 3.125 BID

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7
Q

What is the target dosing of Coreg for HFrEF?

A

<85 kg = 25 BID
>85 kg = 50 BID

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8
Q

What is the counseling of Coreg for HFrEF?

A

Take with food to avoid orthostasis

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9
Q

What is the dosing of Coreg SR for HFrEF?

A

Start: 10 QD
Target: 80 QD

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10
Q

How often do you titrate Coreg/SR for HFrEF?

A

Titrate the dose every 2 weeks until you reach the highest tolerated amount

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11
Q

What is the dosing of Lanoxin Tablets for HFrEF/AFib with Flutter?

A

0.125 - 0.25 QD

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12
Q

Do you give a loading dose of Lanoxin Tablets?

A

Yes in AFib, then it is reduced to 0.125-0.25 maintenance dosing range

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13
Q

What is the dosing of Isosorbide Dinitrate for Chronic Angina?

A

TID

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14
Q

What times do you dose Isosorbide Dinitrate for Chronic Angina?

A

7-12-5 for nitrate free intervals

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15
Q

What is the dosing of Isosorbide Dinitrate ER for Chronic Angina?

A

BID

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16
Q

What times do you dose Isosorbide Dinitrate ER for Chronic Angina?

A

8-2 for nitrate free interval

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17
Q

What is the dosing of Imdur for Chronic Angina?

A

QD

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18
Q

When do you dose Imdur for Chronic Angina?

A

AM

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19
Q

What is the dosing of Nitrostat for Angina?

A

SL tablet, Q5 min up to 3 doses prn

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20
Q

What is the dosing of Apresoline for HTN?

A

BID - QID

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21
Q

What is the concern with Apresoline?

A

Doses >200 mg/day may high higher risk of lupus like reactions

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22
Q

What is the dosing of Plavix for ACS?

A

75 QD

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23
Q

What is Brillinta dosed for and its caution?

A

ACS, use with ASA doses no greater than 75-100 mg QD

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24
Q

What is Pletal dosed for and its caution?

A

Intermittent Claudication, 2-12 wk trial (up to 12 wk for max effect), AVOID grapefruit

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25
Q

What is the dosing of Coumadin for AFib or VTE?

A

2-10 mg QD

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26
Q

What is the dosing of Pradaxa for DVT/PE Prevention and Treatment?

A

BID

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27
Q

What is the caution of Pradaxa for DVT/PE Prevention and Treatment?

A

Initiated after 5-10 days of parental anticoagulant, AVOID if CrCl <30

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28
Q

What is the dosing of Pradaxa for Stroke Prevention in Nonvalvular AFib?

A

BID

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29
Q

What is the caution of Pradaxa for Stroke in Nonvalvular AFib?

A

Dose adjust if CrCl 15-30, AVOID if <15

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30
Q

What is the dosing of Xarelto for DVT/PE Prevention and Joint Replacement?

A

10 QD

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31
Q

What is the caution of Xarelto for DVT/PE Prevention?

A

AVOID if CrCl <30

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32
Q

What is the dosing of Xarelto for DVT/PE Treatment?

A

15 BID x 21 days
20 QD after

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33
Q

What is the caution for Xarelto for DVT/PE Treatment?

A

Take with food for doses >15mg
AVOID if CrCl <30

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34
Q

What is the dosing of Xarelto for Stroke Prevention in Nonvalvular AFib?

A

20 QD with evening meal

35
Q

What is the caution of Xarelto for Stroke Prevention in AFib?

A

Dose adjust if CrCl 15-50
AVOID if <15

36
Q

What is the dosing of Eliquis in DVT/PE Prevention and Joint Replacement?

A

2.5 mg BID
Begin 12-24 hrs post op

37
Q

What is the therapy duration for Joint Replacement?

A

HIP = 35 days
KNEE = 12 days

38
Q

What is the dosing of Eliquis for DVT/PE Treatment?

A

10 mg BID x 7 days
5 BID after

39
Q

What is the duration of Eliquis for DVT/PE Treatment?

A

2.5 BID for 6 MONTHS

40
Q

What is the dosing of Eliquis for Stroke Prevention in Nonvalvular AFib?

41
Q

What is the caution of Eliquis for Stroke in AFib?

A

Reduce to 2.5 BID if any 2 of the following are present:
1. >80 yrs
2. Weight <60kg
3. Serum Creatinine >1.5
May Consider if CrCl <15

42
Q

What is the dosing of Savaysa for DVT/PE Treatment?

43
Q

What is the caution of Savaysa for DVT/PE Treatment?

A

Initiate after 5-10 days of parenteral anticoagulant
Reduce dose if <60 kg
Dose adjust if CrCl 15-50
AVOID <15

44
Q

What is the dosing of Savaysa for Stroke Prevention in AFib?

45
Q

What is the caution of Savaysa for Stroke Prevention in AFib?

A

Dose adjust if CrCl 15-50
AVOID if <15 or >95

46
Q

What is Zaroxolyn dosed for and its caution?

A

Edema due to CHF, used as 2nd diuretic sometimes dosed every other day

47
Q

What is the dosing of Aldactone for HFrEF?

A

Start: 12.5 QD
Target: 25 QD

48
Q

What is the caution of Aldactone for HFrEF?

A

AVOID CrCl <30

49
Q

What is the dosing of Inspra for HFrEF POST MI?

A

Start: 25 QD
Target: 50 QD

50
Q

What is the dosing of Corlanor for HFrEF with EF <35%?

A

Start: 2.5-5 BID
Target: 7.5 BID

51
Q

Why use Corlanor for HFrEF with EF <35% and what is its titration criteria?

A

To decrease hospitalizations and titrate HR 50-60 bpm

52
Q

What is the dosing of Entresto for HFrEF?

A

Start: 24/26 BID
Target: 97/103 BID

53
Q

What is the caution for Entresto for HFrEF?

A

Reduce dose if eGFR >30

54
Q

What is the dosing of Altace for HFrEF?

A

Start: 1.25 - 2.5 QD
Target: 10 QD

55
Q

What is the dosing of Capoten for HFrEF?

A

Start: 12.5 - 25 BID/TID
Target: 50 TID

56
Q

What is the dosing of Vasotec for HFrEF?

A

Start: 2.5 BID
Target: 10-20 BID

57
Q

What is the dosing of Zestril for HFrEF?

A

Start: 2.5-5 QD
Target: 40 QD

58
Q

When can you dose Zestril BID?

59
Q

What is the dosing of Atacand for HFrEF?

A

Start: 4-8 QD
Target: 32 QD

60
Q

What is the dosing of Cozaar for HFrEF?

A

Start: 25-50 QD
Target: 150 QD

61
Q

What is the caution of Cozaar for HFrEF?

A

Lower initial dose in hepatic disease

62
Q

What is the dosing of Diovan for HFrEF?

A

Start: 20-40 BID
Target: 160 BID

63
Q

What is the dosing of Norvasc for HTN?

64
Q

What is the dosing of Norvasc for Vasopastic/Chronic Stable Angina?

65
Q

When do titrate dosing for Cardura in HTN?

A

Titrate Q1-2 wks, re-titrate to avoid syncope

66
Q

When do you titrate dosing for Hytrin in HTN?

A

Re-titrate if therapy interrupted

67
Q

What is the dosing of Catapres for HTN?

A

0.2 - 0.6 QD in 2 divided doses

68
Q

When do you titrate Catapres for HTN?

A

Initial dose of 0.1 BID, can increase to 0.1 mg/day increments at weekly intervals

69
Q

What is the dosing of Catapres TTS for HTN?

A

0.1 - 0.3 mg/day patch applied every 7 days

70
Q

What is the caution of Catapres TTS for HTN?

A

Onset delayed 2-3 days after intiation

71
Q

When should you titrate Mevacor, Pravachol, and Zocor for Dyslipdemia/ACS Prevention?

A

Titrate Q 4-6 weeks; dose with evening meal

72
Q

What statin has a 80 mg/day dosage restriction?

73
Q

What is the patient counseling of Lopid for Hypertriglycerdemia >500?

A

Take on empty stomach 30 mins before morning and evening meals

74
Q

What is the dose of Tricor for Hypertriglycerdemia >500?

75
Q

What is the caution of Tricor for Hypertriglycerdemia >500?

A

CI if CrCl <30

76
Q

What is the caution of Trilipix for Hypertriglycerdemia >500?

A

CI if CrCl <30

77
Q

What is the titration schedule of Question for Hypertriglycerdemia LDL Lowering?

A

Titrate Q 4-6 weeks

78
Q

What is the dosing of Niaspan for Hypertriglycerdemia >500?

A

500 - 2000 mg Q HS with snack

79
Q

What is the titration of Niapsan for Hypertriglycerdemia >500?

A

Extended Release; titrate 500 mg Q4 weeks to response

80
Q

What is the dosing for Zetia for Hypertriglycerdemia LDL Lowering

81
Q

When do you take Vytorin for Hypertriglycerdemia LDL Lowering

A

Taken in the evening

82
Q

What is the dosing for Lovaza for Hypertriglycerdemia >500?

A

4 caps QD or 2 caps BID

83
Q

What is the counseling for Lovaza for Hypertriglycerdemia >500?

A

1 cap = 1 g, take with food

84
Q

What is the dosing of Cordarone for AFib?

A

100-200 QD

Pharmacy Practice V (19 decks)

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