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Pharmacy Practice V > Atrial Fibrillation Medications > Flashcards

Atrial Fibrillation Medications Flashcards

1
Q

What is the indication for Amiodarone?

A

AF, Ventricular Arrhythmias

Off: Supraventricular Arrhythmias

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2
Q

What class is Amiodarone?

A

Class III Antiarrhythmic

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3
Q

What are DDIs of concern for Amiodarone?

A

Digoxin and Warfarin

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4
Q

What are the CIs of Amiodarone?

A
  1. Sick sinus syndrome
  2. Bradycardia leading to syncope
  3. Cardiogenic shock
  4. 2nd and 3rd degree AV block
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5
Q

What is the dermatologic toxicity concern with Amiodarone?

A

Blue Gray Discoloration

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6
Q

What are the Black Box warning for Amiodarone?

A

Hepatotoxicity
Pulmonary Toxicity: Pneumonitis

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7
Q

Can Amiodarone cause QTc Prolongation?

A

YES

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8
Q

What labs should be monitored when taking Amiodarone?

A

CXR, PFTs, LFTs, and TSH

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9
Q

What is a counseling point for Amiodarone?

A

Avoid grapefruit

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10
Q

What are the indications for Dofetilide?

A

AFib/Flutter and Supraventricular Tachycardia

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11
Q

What class is Dofetilide?

A

Class III Antiarrhythmic

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12
Q

What are the AEs of Dofetilide?

A
  1. HA
  2. Chest Pain
  3. Tachycardia
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13
Q

When should you dose adjust with Dofetilide?

A

CrCl <60

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14
Q

What are the warnings for Dofetilide?

A

Arrhythmias
QTc Prolongation
Torsades de Pointes

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15
Q

What is the initiation process of Dofetilide?

A

Must be inpatient for 3 days during initiation and reinitiating of therapy

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16
Q

What are the CIs of Dofetilide?

A
  1. Congential or Acquired long QT
  2. Baseline QTc >440 or >500
  3. CrCl <20
17
Q

What are the major DDIs of Dofetilide?

A
  1. HCTZ
  2. Verapamil
18
Q

What is the indication for Flecainide?

A

AFib/Flutter, Ventricular Arrhytmias

19
Q

What class is Flecainide?

A

Class Ic Antiarrhythmic

20
Q

What are the AEs of Flecainide?

A

Ventricular Arrhythmia
Dizzy
Visual Disturbances

21
Q

What are the CIs of Flecainide?

A
  1. 2nd-3rd degree AV block or RBBB
  2. Cardiogenic Shock
  3. Concomitant use of Ritonavir
  4. Structural Heart Disease = AVOID in HF

Pharmacy Practice V (19 decks)

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