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Pharmacy Practice V > Diuretics > Flashcards

Diuretics Flashcards

1
Q

What is the Loop Diuretic Conversion?

A

Furosemide 20 IV = Furosemide 40 PO = Toresmide 20 IV/PO = Bumetanide 1 IV/PO

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2
Q

What are the indications for Diuretics?

A

HTN and Edema

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3
Q

What drugs are effective for HTN and Edema?

A

HTN: Thiazides/Aldosterone
Edema: Loop

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4
Q

Chlorthalidone has the longest half life but in return has what?

A

Most electrolyte wasting

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5
Q

When is HCTZ less effective?

A

CrCl <30

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6
Q

Which Aldosterone Antagonist is more selective for mineralocorticoid receptors?

A

Eplereone = less gynecomastia

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7
Q

What are the Loop Diuretics?

A

Furosemide, Torsemide, and Bumetanide

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8
Q

What are the Thiazides/Like Diuretics?

A

HCTZ, Indapamide, Metolazone, and Chlorthalidone

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9
Q

What are the Potassium-Sparing Diuretics?

A

Triamterene, Spironolactone, and Eplerenone

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10
Q

When should you check serum potassium for Potassium-Sparing Diuretics?

A

Within 3 days of starting then 1 weeks, and then monthly for 3 months

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11
Q

What is the indication of Lasix?

A

Edema, HTN, and Ascites

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12
Q

hat is the indication of Bumex?

A

Edema

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13
Q

What is Dyazide?

A

Hydrochlorothiazide 25 mg/triamterene 37.5 mg: CAPSULES

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14
Q

What is Maxzide?

A

Hydrochlorothiazide 50 mg/triamterene 75 mg: TABLET

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15
Q

What is the indication of Demadex?

A

Edema and HTN

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16
Q

What is the indication of HCTZ?

A

Edema and HTN

17
Q

What is the indication for Indapamide?

A

Edema and HTN

18
Q

What is the indication of Chlorthalidone and its half life?

A

Edema and HTN
40-60 hrs

19
Q

What is the indication of Metolazaone?

20
Q

When Metolazone is combined with Loops what is the precaution?

A

Enhanced diuresis, close monitoring needed

21
Q

What is the indication of Aldactone?

A

HTN, HFrEF, Primary Aldosteronism, Cirrhosis

22
Q

What DDIs are there with Aldactone?

A

ACE, Potassium Sparing Meds, and Potassium Supplements

23
Q

What are the CIs of Aldactone?

A

Anuria/Renal Insufficiency, and Hyperkalemia

24
Q

What is the indication of Inspra?

A

HF post MI and HTN

25
Q

What drugs can increase serum levels of Inspra?

A

Diltiazem and Verapamil

26
Q

What are the CIs of Eplerenone?

A
  1. Serum Potassium >5.5
  2. CrCl <30
  3. Clarithromycin
  4. Itraconazole
  5. HTN + Type2 DM
  6. HTN + SCr >2 or >1.8
  7. HTN + CrCl <50
27
Q

When should use of Maxzide and Dyazide be cautioned?

A

Patients with kidney stones

28
Q

What drugs cause Hypercalemia?

29
Q

What drugs cause Hyperuricemia?

A

Loops, Thiazides, and Spironolactone

30
Q

What drugs cause Otoxoticity?

31
Q

What drugs cause Ocular Effects?

32
Q

What drugs cause Photosensitivity?

A

Thiazides mostly, maybe loops

33
Q

What drugs cause Hypokalemia?

A

Loops and Thiazides

34
Q

What drugs cause Hypomagnesemia and Hyponatremia?

A

Loops and Thiazides

Pharmacy Practice V (19 decks)

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