Diuretics

Question 1

What is the Loop Diuretic Conversion?

Answer 1

Furosemide 20 IV = Furosemide 40 PO = Toresmide 20 IV/PO = Bumetanide 1 IV/PO

Question 2

What are the indications for Diuretics?

Answer 2

HTN and Edema

Question 3

What drugs are effective for HTN and Edema?

Answer 3

HTN: Thiazides/Aldosterone
Edema: Loop

Question 4

Chlorthalidone has the longest half life but in return has what?

Answer 4

Most electrolyte wasting

Question 5

When is HCTZ less effective?

Answer 5

CrCl <30

Question 6

Which Aldosterone Antagonist is more selective for mineralocorticoid receptors?

Answer 6

Eplereone = less gynecomastia

Question 7

What are the Loop Diuretics?

Answer 7

Furosemide, Torsemide, and Bumetanide

Question 8

What are the Thiazides/Like Diuretics?

Answer 8

HCTZ, Indapamide, Metolazone, and Chlorthalidone

Question 9

What are the Potassium-Sparing Diuretics?

Answer 9

Triamterene, Spironolactone, and Eplerenone

Question 10

When should you check serum potassium for Potassium-Sparing Diuretics?

Answer 10

Within 3 days of starting then 1 weeks, and then monthly for 3 months

Question 11

What is the indication of Lasix?

Answer 11

Edema, HTN, and Ascites

Question 12

hat is the indication of Bumex?

Answer 12

Edema

Question 13

What is Dyazide?

Answer 13

Hydrochlorothiazide 25 mg/triamterene 37.5 mg: CAPSULES

Question 14

What is Maxzide?

Answer 14

Hydrochlorothiazide 50 mg/triamterene 75 mg: TABLET

Question 15

What is the indication of Demadex?

Answer 15

Edema and HTN

Question 16

What is the indication of HCTZ?

Answer 16

Edema and HTN

Question 17

What is the indication for Indapamide?

Answer 17

Edema and HTN

Question 18

What is the indication of Chlorthalidone and its half life?

Answer 18

Edema and HTN
40-60 hrs

Question 19

What is the indication of Metolazaone?

Answer 19

Edema

Question 20

When Metolazone is combined with Loops what is the precaution?

Answer 20

Enhanced diuresis, close monitoring needed

Question 21

What is the indication of Aldactone?

Answer 21

HTN, HFrEF, Primary Aldosteronism, Cirrhosis

Question 22

What DDIs are there with Aldactone?

Answer 22

ACE, Potassium Sparing Meds, and Potassium Supplements

Question 23

What are the CIs of Aldactone?

Answer 23

Anuria/Renal Insufficiency, and Hyperkalemia

Question 24

What is the indication of Inspra?

Answer 24

HF post MI and HTN

Question 25

What drugs can increase serum levels of Inspra?

Answer 25

Diltiazem and Verapamil

Question 26

What are the CIs of Eplerenone?

Answer 26

1. Serum Potassium >5.5
2. CrCl <30
3. Clarithromycin
4. Itraconazole
5. HTN + Type2 DM
6. HTN + SCr >2 or >1.8
7. HTN + CrCl <50

Question 27

When should use of Maxzide and Dyazide be cautioned?

Answer 27

Patients with kidney stones

Question 28

What drugs cause Hypercalemia?

Answer 28

Thiazides

Question 29

What drugs cause Hyperuricemia?

Answer 29

Loops, Thiazides, and Spironolactone

Question 30

What drugs cause Otoxoticity?

Answer 30

Loops

Question 31

What drugs cause Ocular Effects?

Answer 31

HCTZ

Question 32

What drugs cause Photosensitivity?

Answer 32

Thiazides mostly, maybe loops

Question 33

What drugs cause Hypokalemia?

Answer 33

Loops and Thiazides

Question 34

What drugs cause Hypomagnesemia and Hyponatremia?

Answer 34

Loops and Thiazides