Cardiovascular Drugs Flashcards
Drug that accelerate the rate of urine formation that results to the removal of sodium and water from the body
Diuretics
Works on the collecting ducts and DCT by blocking the aldosterone receptor
Potasisum-Sparing
Acts on the brain by decreasing NE production
Central Acting
At the heart and blood vessels
Peripheral Acting
Severe hypotension resulting to loss of consciousness
First Dose Syncope
Minoxidil
Effectiveness in restoring hair growth
Minoxidil
Both arterial and venous vasodilation
Nitroprusside
From spasms of the smooth muscle that surrounds the coronary arteries and occurs at rest without any triggers but usually occurring at the same time of day
Vasospastic Angina
Pathologic state in which the heart is unable to pump in sufficient amounts from the ventricles to meet metabolic needs
Heart Failure
Increase the force of myocardial contraction
Positive Inotropic drugs
Accelerate conduction
Positive Dromotropic drugs
Oldest group of cardiac drugs, came from foxglove or digitalis plant
Cardiac Glycosides
Low K or Mg and declining renal function may increase potential for _______
Toxicity
Given parenterally over 30 minutes, refrigerated, use immediately after mixed. If not used withing 4hrs discard. Monitor for A/E
Digoxin Immune Fab