Cardiopulmonary Flashcards
apex (heart)
lowest part of the heart formed by the inferolateral part of the left ventricle. It projects anteriorly and to the left at the level of the 5th intercostal space and the left midclavicular line.
base (heart)
the upper border of the heart involving the left atrium, part of the right atrium, and the proximal portions of the great vessels. It lies approximately below the second rib at the level of the 2nd intercostal space.
endocardium
the endothelial tissue that lines the interior of the heart chambers and valves.
epicardium
the serous layer of the pericardium. The epicardium contains the epicardial coronary arteries and veins, autonomic nerves, and lymphatics
myocardium
the thick contractile middle layer of muscle cells that forms the bulk of the heart wall
pericardium
a double-walled connective tissue sac that surrounds the outside of the heart and great vessels
aorta
body’s largest artery and the central conduit of blood from the heart to the body.
inferior vena cava
the vein that returns venous blood from the lower body and viscera to the right atrium
pulmonary arteries
the arteries that carry deoxygenated blood from the right ventricle to the left and right lungs
pulmonary veins
the veins that carry oxygenated blood from the right and left lungs to the left atrium
superior vena cava
the vein that returns venous blood from the head, neck, and arms to the right atrium
atrial systole
contraction of the right and left atria pushing blood into the ventricles
atrial diastole
the period between atrial contractions when the atria are repolarzing
ventricular systole
contraction of the right and left ventricles pushing blood into the pulmonary arteries and aorta
ventricular diastole
the period between ventricular contractions when the ventricles are repolarizing
preload
refers to the tension in the ventricular wall at the end of diastole.
Reflects the venous filling pressure that fills the left ventricle during diastole.
afterload
refers to the forces that impede the flow of blood out of the heart, primarily the pressure in the peripheral vasculature, the compliance of the aorta, and the mass and viscosity of the blood
stroke volume (SV)
refers to the volume of blood ejected by each contraction of the left ventricle.
Normal SV ranges from 60 to 80 mL depending on age, sex, and activity
cardiac output (CO)
the amount of blood pumped from the left or right ventricle per minute. It is equal to the product of SV and HR. (CO = HR x SV)
Normal CO for adult male at rest = 4.5-5.0 L/min with women producing slightly less.
CO can increase up to 25 L/min during exercise
venous return
amount of blood that returns to the right atrium each minute. This is similar in volume to the CO.
Because the cardiovascular system is a closed loop, venous return must equal CO when averaged over time.
hypovalemia
decreased blood volume, specifically the volume of plasma
hypervalemia
“fluid overload” - increased blood plasma
neutrophils
help protect the body against infections by ingesting bacteria and debris
lymphyocytes
consist of 3 main types - T lymphocytes and natural killer cells that help protect against viral infections and can detect and destroy some cancer cells, and B lymphocytes, which develop into cells that produce antibodies
monocytes
ingest dead or damaged cells and help defend against infectious organisms
eosinophils
kill parasites, destroy cancer cells, and are involved in allergic responses
basophils
participate in allergic responses
baroreceptors
mechanoreceptors that detect changes in pressure
arterial baroreceptors
high pressure receptors located in the carotid sinus, aortic arch, and origin of the right subclavian artery
Cardiopumonary receptors
low pressure receptors
acidemia
elevated acidity of blood (pH < 7.35)
alkalemia
decreased acidity of blood (pH > 7.45)
eucapnia
normal level of CO2 in arterial blood (PaCO2 35-45 mmHg)
hypercapnia
elevated level of CO2 in arterial blood (PaCO2 > 45 mmHg)
hypocapnia
low level of CO2 in arterial blood (PaCO2 < 35 mmHg)
hypoxemia
low level of O2 in arterial blood (PaO2 < 80 mmHg)
mild hypoxemia
PaO2 60-79 mmHg
moderate hypoxemia
PaO2 40-59 mmHg
severe hypoxemia
PaO2 < 40 mmHg
hypoxia
low level of O2 in the tissue despite adequate perfusion of the tissue
polycythemia vera
condition that causes overproduction of RBC’s
Bronchophony
Increased vocal resonance with greater clarity and loudness of spoken words (e.g., “99”)
egophony
A form of bronchophony in which the spoken long “E” sound changes to a long, nasal-sounding “A”
whispered pectoriloquy
recognition of whispered words “1,2,3”
normal sinus rhythm
atrial depolarization begins in the SA node and spreads normally throughout the electrical conduction system with a heart rate between 60 and 100 bpm
sinus bradycardia
sinus rhythm with a heart rate of < 60 bpm (in adults)
sinus tachycardia
sinus rhythm with a heart rate of > 100 bpm (in adults)
sinus arrhythmia
a sinus rhythm, but with quickening and slowing of impulse formation in the SA node resulting in a slight beat-to-beat variation of the rate
sinus arrest
a sinus rhythm, except with intermittent failure of either SA node impulse formation or AV node conduction that results in the occasional complete absence of P or QRS waves
bigeminy
normal sinus impulse followed by a PVC
trigeminy
PVC occurs after every 2 normal sinus impulses
stable angina
occurs at a predictable level of exertion, exercise, or stress and responds to rest or nitroglycerin
unstable angina
usually is more intense, lasts longer, is precipitated by less exertion, occurs spontaneously at rest, is progressive, or any combination of these features
Prinzmetal (varient) angina
occurs due to coronary artery spasm most often associated with coronary artery disease
septal myectomy
removal of thickened interventricular septum
used in treatment of hypertrophic cardiomyopathy
septal alcohol ablation
destruction of the interventricular septum by alcohol injection
used in treatment of hypertrophic cardiomyopathy
Anatomic Dead Space Volume
The volume of air that occupies the non-respiratory conducting airways.
Expiratory Reserve Volume
The maximal volume of air that can be exhaled after a normal tidal exhalation.
ERV is approximately 15% of total lung volume.
Forced Expiratory Volume
The maximal volume of air exhaled in a specified period of time: usually the 1st, 2nd, and 3rd second of a forced vital capacity maneuver.
Forced Vital Capacity
The volume of air expired during a forced maximal expiration after a forced maximal inspiration.
Forced Residual Capacity
The volume of air in the lungs after normal exhalation.
FRC = ERV + RV.
FRC is approximately 40% of total lung volume.
Inspiratory Capacity
The maximal volume of air that can be inspired after a normal tidal exhalation.
IC = TV + IRV.
IC is approximately 60% of total lung volume.
Inspiratory Reserve Volume
The maximal volume of air that can be inspired after normal tidal inspiration.
IRV is approximately 50% of total lung volume.
Minute Volume Ventilation
The volume of air expired in one minute
VE = TV + respiratory rate.
Peak Expiratory Flow
The maximum flow of air during the beginning of a forced expiratory maneuver.
Residual Volume
The volume of gas remaining in the lungs at the end of a maximal expiration.
RV is approximately 25% of total lung volume.
Tidal Volume
Total volume inspired and expired with each breath during quiet breathing.
TV is approximately 10% of total lung volume.
Total Lung Capacity
The volume of air in the lungs after a maximal inspiration; the sum of all lung volumes.
TLC = RV + VC
TLC = FRC + IC
Vital Capacity
The volume change that occurs between maximal inspiration and maximal expiration.
VC = TV + IRV + ERV.
VC is approximately 75% of total lung volume.
apnea
absence of spontaneous breathing
Biot’s (breathing pattern)
irregular breathing; breaths vary in depth and rate with periods of apnea; often associated with increased ICP or damage to the medulla
bradypnea
slower than normal respiratory rate ( < 12 breaths/min in adults); may be associated with neurologic or electrolyte disturbance, infection, or high level of cardiorespiratory fitness
Cheyne-Stokes (periodic)
breathing pattern
decreasing rate and depth of breathing with periods of apnea; can occur d/t CNS damage
eupnea
normal rate and depth of breathing
hyperpnea
increased rate and depth of breathing
hypopnea
decreased rate and depth of breathing
Kussmaul’s (breathing pattern)
deep and fast breathing; often associated with metabolic acidosis
paradoxical (breathing pattern)
chest wall moves in with inhalation and out with exhalation; due to chest trauma or paralysis of the diaphragm
tachypnea
faster than normal respiratory rate ( > 20 breaths/min in adults)