Cardiomyopathy Flashcards
major classification of cardiomyopathy
dilated
restrictive
hypertrophic
most common pattern of Familial cardiomyopathy
autosomal dominant
EF For each cardiomyopathy
Dilated:< 30%
Restrictive: 25-50%
Hypertrophic:>60%
Tx for long standing cardiomyopathy
BB + ACEI/ARB
Most common cause of infective myocarditis
Trypanosoma cruzi
Protein degraded by viral proteases in viral myocarditis during myocardial injury and lysis
Dystrophin
Rapid progression from severe febrile resp infection to cardiogenic shock and MOD
Acute fulminant myocarditis
Diagnosis of viral myocarditis according to Dallas criteria
Lymphocytic infiltration with evidence of myocyte necrosis (negative in 80-90%)
Clinical findings of pericarditis + elevated cardiac markers or abnormal wall motion
Perimyocarditis/ myopericarditis
Viruses implicated in myocarditis
HIV, Hep C
Therapy for toxoplasmosis
Pyrimerhamine + sulfadiazene/ clindamycin
Most common cause of non infectious myocarditis
Granulomatous (sarcoidosis, giant cell)
Risk factors for peripartum cardiomyopathy
Increased maternal age Increased parity Malnutrition Twin pregnancy Use of tocolytic therapy Preeclampsia Toxemia of preg
Most common toxin implicated in toxic cardiomyopathy
Alcohol
Chemotherapeutic agents implicated in cardiomyopathy
Anthracyclines, trastuzumab, cyclophosphamide, ifosphamide
