Cardiology Flashcards
What breed is predisposed to myxomatous degenerative valve disease (MDVD)
cavalier king charles spaniel
middle aged small breeds generally
cause is idiopathic
what are the three main cardiac diseases affecting dogs
- MDVD
- DCM
- ARVC
describe MDVD
nodular thickening of the valves leaflets mostly affecting the mitral valve. The chordae become lengthened or ruptured
what is the gross pathology of MDVD
LA and LV dilation from chronic volume overload leading to eccentric hypertrophy.
Thickened leaflets
what are the staging of MDVD
A=at risk
B1=murmur, no enlargement
B2=murmur, enlargement
C1=CHF, hospitalised
C2=CHF, at home
D1=refractory, hospitalised
D2=refractory, at home
what are diagnostics used to investigate MDVD
blood pressure
bloods: NT-proBNP levels increased by atrial stretch
ECG: P mitrale, tall R waves
echocardiographyw
what is the treatment for MDVD
pimobendan if in stage B2
Furosemide for stages C and D
*Once in CHF lifespan usually <1 year
Define canine dilated cardiomyopathy
A primary myocardial disorder characterised by dilation of all 4 cardiac chambers and reduced contractility
what breeds are predisposed to DCM
dobermans, grate dane
what is the gross pathology of DCM
all chambers enlarged but left ventricle mostly dilated.
mitral/tricuspid annulus stretched and pulled apart
what are the consequences of dcm
- reduced cardiac output
- RAAS+sympathetic activation
- increase in HR and contractility
- increase in oxygen demand and wall stress
- myocardial cell death
what is the treatment for DCM
Pimobendan and ace inhibitor.
furosemide added once CHF is started
what causes DCM in cats
taurine deficiency
What are the diiferences between MDVD and DCM
- MDVD has significant mitral regurg, DCM has mild
- DCM has reduced systolic function, MDVD has normal
- MDVD left atrium more enlarged than left ventricle. DCM left ventricle more enlarged than left atrium
Described Arrythmogenic right ventricular cardiomyopathy
progressive loss of myocytes with fibrofatty replacement
what breeds are predisposed to ARVC
Boxer breeds
disease also known as boxer cardiomyopathy
what is the pathology of ARVC
right ventricular dilation with wall thinning
what are the three presentations of ARVC
- asymptomatic with VPCs
- Symptomatic with VPCs
- structural changes to the heart with arrythmias