Cardio Flashcards
Phospholamban increase or decrease leads to contractility ?
decrease ( its phosphorylation leads to its inactivation
contractility depends on 2 entities
size of the inward current I
amount of Ca from previous beats
lysitropy
myocardial relaxation
Verapamil is nondihydro or dihydro?
non-dihydro
increase in afterload will lead to increase in wall _____.sho besir to decrease hal increase
wall tension
heart hypertrophies to decrease the wall tension
how is afterload approximated?
MAP
increase or decrease in extracellular Na will lead to contractility
decrease . krml el Na/Ca channel . less na out. less na rah eyfut so less Ca rah yedhar
flow
pressure/resistance = V x A
lowest flow velocity is found in what vessels?
cappillary (because they have the highest surface area)
compliance formula
C = V/P
when we are measuring the Pul wedge pressure ka2ano we are measuring the
LAP
parasympathetic innervation of the heart is to?
atria
dromotropic
conduction
frank starling
increase in volume –> increase in ventricular muscle fiber –> increase in developed tension
period of highesr O2 consumption in the pressure-volume loop/
isovolumetric contraction
S3 in a young individual is
normal in children- young adults - and pregnant woman
S4 in elderly individual is
always abnormal regardless of the age of the patient.
the y descent sho fe pathologies
prominent in constrictive pericarditis and absent in cardiac tamponade .
clamping of abdominal artery lead to
increase afterload
what 2 things increase TPR and what decrease TPR
and what is shift shape like ( clock)
increase TPR : vasopressors - clockwise
decrease TPR : exercise and AV shunt - counterclockwise
can we determine easily the RAP in decrease or increase in TPR ? without using the graph? why
No le2ano masalan , increase in TPR –> decrease CO -> increase RAP
increase in TPR –> decrease in VR –> deccrease RAP
so we cannot expct this , we need the graph