Cardio Flashcards
CHF findings on CXR
Kerley B-lines Vascular redistribution Cardiomegaly Peribronchial cuffing Perihilar infiltrates Pleural effusion
Galactin-3-mediated heart failure
Galectin-3 instigates fibrosis after cardiac ischemia or MI –> a/w heart remodelling, increased stiffening of heart which reduces cardiac output = heart failure
Pulmonary capillary wedge pressure in cardiogenic pulmonary edema
> 25mmHg
Pulmonary capillary wedge pressure in ARDS-induced pulmonary edema
<18mmHg
Cheyne-Stokes respirations
Triggered by hyperventilation and hypocapnia
Form of periodic breathing in which central apneas and hypopnea alternate with periods of hyperventilation –> waxing and waning of tidal volume
PE on ECG
Sinus tachy New RAD Complete or incomplete RBBB Dominant R wave in V1 (RV dilatation) S1Q3T3 pattern Deep S in lead I Q wave in lead III Inverted T wave in lead III
Tx for MI
B-MONAA + PCI/thrombolysis
Betablocker
Morphine
O2
Nitro (beware in RH infarction ie. inferior or posterior)
Antiplt (ASA 320mg + Clopidogrel for PCI or Ticagrelor if more invasive)
Anticoag (UFH if PCI, LMWH if thrombolysis)
PCI if door to balloon time <90 min and within 12h of symptom onset
Thrombolysis (Alteplase) if no C/I and within 12h of symptom onset
Septal MI
V1, V2
LAD
Anterior MI
V3, V4
LAD
Anterolateral MI
V5, V6
LAD
Inferior MI
II, III, aVF
RCA (Lead III ST elevation > Lead II, ST depression in I and AVL)
LCx (ST elevation in II is equal to that in III + ST segment depression in V1-V3)
Lateral MI
I, aVL
LCx
Posterolateral MI
V7, V8, V9
RCA
Normal QTc length in men and women
Men: <450
Women <460
Hypertrophic cardiomyopathy P/E
Double apical pulse (forceful LA contraction against highly noncompliant LV)
Carotid bifid pulse (rises quickly b/c increased velocity of blood through LV outflow tract into aorta, then declines in mid-systole as gradient develops)
Increased murmur on Valsalva
HOCM tx
Main goal is symptomatic relief
Beta blockers = reduce ventricular contractility, increased ventricular volume, compliance and reduce pressure gdt across LV outflow tract
AVOID drugs that REDUCE preload (ie. ACEi, diuretics, nitrates)
HOCM mostly affects ___ side of heart
Left
Left sided murmurs increase by conditions that increase _____ and decrease by conditions that decrease ______
Increase by increased preload
Decrease by deccreased preload
Ie. Aortic stenosis murmur is increased by rapid leg raising/squatting, but is decreased by valsalva/standing
3 characteristics of WPW syndrome on ECG
Shortened PR interval (<0.12s) Slurred upstroke of R-wave Broadened QRS (>100ms)
HOCM characteristics on ECG
T wave inversion ST segment depression Pathological Q waves Conduction delay LAD LAE
Debakey aortic dissection classifcation
BAD
I = both ascending and descending
II = ascending only
III = descending only
Stanford aortic dissection classification
A = ascending +/- descending B = descending only
Stanford A aortic dissection tx
Medical preferred (HTN mgmt) unless ruptured
Stanford B aortic dissection tx
Surgery
CHADS score
Stroke risk assessment in AFib pt CHF (1) HTN (1) Age >/=75 (1) Diabetes mellitus (1) Stroke/TIA (2)
1 : OAC needed depends
>/=2 : OAC
If CHADS 0 and NO CAD OR arterial vascular dz, NO ASA needed
Meds used in cardiac arrest algorithm
Epi 1mg IV q3-5min
Amiodarone 300mg IV (for VT/VF that’s unresponsive to shock, CPR and vasopressor)
1st degree AV block
PR interval >200ms
CONSTANT
No tx required
2nd degree AV block: Mobitz Type 1 (Wenkebach)
PR interval progressively increases until failed conduction
Usually A/W AV node disease
2nd degree AV block: Mobitz Type 2
Constant PR, either normal or prolonged with RANDOM failures
Usually A/W His Bundle disease
Worse than Type I
3rd degree AV block
Complete AV dissociation
Main medications used in bradycardia algorithm
Atropine 0.5mg IV q3-5min to total of 3mg
If atropine fails –> dopamine 2-20mcg/kg/min OR epi 2-10mcg/min
Tx of choice in symptomatic brady pt with poor perfusion
Transcutaneous pacing
Start at 60/min and adjust by pt response
Synchronized CV dose if narrow and regular tachycardia
50-100J
Use in atrial flutter, SVT
Synchronized CV dose if narrow and irregular
150-200J biphasic or 200J monophasic
Use in afib
Synchronized CV dose if wide and irregular
100J
Use in monomorphic VT
CV dose if wide and irregular
Defibrillator dose
NOT synchronized
Pulseless VT/VF
Atropine
Blocks vagus nerve –> increased SA node discharge –> increased HR
Adenosine
Slows AV node conduction
Tx of choice for regular narrow complex tachy OR monomorphic wide complex, regular tachy
Treatment choice for stable, wide QRS tachy?
Antiarrhythmics (Ie. amiodarone, procainamide, sotalol)
Diameter of ___cm or greater of thoracic aorta is considered aneurysmal
3
Average size of surgically corrected aneurysms
> 5cm
Central Venous Pressure
AKA RA pressure
Pressure in thoracic vena cava near RA
Normal = 0-14cm H2O
Screening for abdominal aortic aneurysm
Smoking men >60-75yo should have an U/S
If high risk (HTN, Marfan’s, Ehlers Danlos syndrome, affected first deg relative), start earlier or at age 60
Framingham Risk Score
10y risk of CAD in pt with dyslipidemia
Target lipid values for high risk framingham
LDL <2
TC:HDL <4
Target lipid values for mod risk framingham
LDL <3.5
TC:HDL <5
Target lipid values for low risk framingham
LDL <5
TC:HDL <6
Aortic stenosis murmur
Crescendo-descrescendo
Ejection click
Diminished or absent A2
Paradoxical splitting of S2 (delayed A2 closure)
Prominent S4
Decreases with valsalva/standing b/c less blood ejected though aortic valve
Increases with squatting b/c increased venous return
Waterhammer pulse
Aortic regurg
Mitral regurg murmur
High pitched holosystolic murmur
Meds for sinus tachy
Beta blocker
CCB if BB C/I
Ivabrudine
Atrial flutter
Reentry tachycardia typically within RA
AV block usually occurs, typically 2:1 (reentry at 300bpm –> 150bpm HR)
Saw tooth pattern on ECG in inferior leads (II, III, aVF), narrow QRS
Tx: electocardioversion if unstable. If stable, rate and rhythm control (BB/CCB/Digoxin + amiodarone/sotalol)
Same anticoag parameters as afib
Multifocal atrial tachycardia
> /= 3 atrial foci, 3 distinct P waves, some not conducted
More common in pts with COPD/hypoxemia
Tx: tx underlying cause, may benefit from CCB (BB often C/I becasue of resp disease)
NO ROLE for electrical cardioversion, antiarrhythmics or ablation
Who should get ASA 81mg?
Pts who have arterial disease (Coronary, aortic or peripheral) but NO CHADS65 risk factors
AVNRT tx
- Vagal maneuvers, carotid sinus pressure
- Adenosine
- Metoprolol, digoxin, diltiazem, electrical CV if unstable
Long term: BB, CCB, digoxin; 2nd line: flecainide, propafenon; 3rd line: catheter ablation
Tx of AFib in WPW
IV procainamide, amiodrone
DO NOT use BB, CCB, Digoxin –> VF
Meds post-MI
ASA 81mg
Ticagrelor or clopidogrel
Beta blocker
Nitro PRN
ACEi (if high risk, symptomatic CHF, reduced LVEF, anterior MI)
Spironolactone (if on ACEi, BB and LVEF <40% and CHF or DM)
Statins (atorvastatin 80mg daily)
Aortic stenosis murmur
Crescendo/decrescendo systolic murmur radiating to R carotid
S4
Aortic regurg murmur
Waterhammer pulse
Early decrescendo diastolic murmur
Mitral stenosis murmur
Mid-diastolic rumble at apex
Mitral regurg murmur
Holosystolic murmur at apex radiating to axilla
Loud S2
S3
Tricuspid stenosis murmur
Diastolic rumble at 4th left intercostal space
Tricuspid regurg murmur
Holosystolic murmur at LLSB
Pulmonary stenosis mumur
Systolic murmur at 2nd left intercostal space
Pulmonary ejection click
Right sided S3
Pulmonary regurg murmur
Early diastolic murmur at LLSB
Mitral valve prolapse murmur
Mid-systolic click (from billowing of mitral leaflet into LA) mid to late systolic murmur at apex
Accentuated by valsalva or squat-to-stand maneuvers
Causes high output heart failure
Anemia
Thyrotoxicosis
AV shunts
C/I to statins
Active liver disease
Persistently high AST and ALT
Wellen’s Syndrome
Deep symmetric T wave inversion in anterior leads
CALL CATH LAB
Hallmark P/E finding of aortic regurg
Wide pulse pressure
(Sys pressure - dias pressure)
Diastolic pressure decreases b/c of decrease flow in aorta
Pulsus arternans
Large pulse followed by small pulse
Seen with severe CHF
Pulsus paradoxus
Exaggeration of normal fall in systolic pressure with inspiration
Normal decrease is <10mmHg
Pulsus paradoxus decrease is 15-20mmHg
Most commonly a/w constrictive or restrictive disease of heart or pericardium
Amiodarone
Similar to thyroxine –> may cause toxic actions
Increased risk of interstitial lung dz due to dramatic decrease in diffusion of CO
= thyroid function tests and pulmonary function tests should be monitored regularly
Receptors a/w dyspnea secondary to pulmonary congestion
J-receptors
BNP and BMI
Lower BMI a/w higher BNP