Cardiff Q - SBA session Flashcards

1
Q

Mechanism of botulinum toxin action

A

Inhibition of Acetyl choline release from pre-junctional axon at neuromuscular junction

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2
Q

Explanation for foetal circulation resulting brain being supplied by blood with higher oxygen content than that supplying the limbs

A

Higher O2 content blood passes through foramen ovale, ejected by left ventricle up the carotids

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3
Q

Electrical voltage and frequency in UK

A

Peak = 340 V

RMS = 240 V
(RMS = Root Mean Squared value)

50 Hz

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4
Q

Absolute risk reduction

A

Control event rate - experimental event rate

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5
Q

Relative risk reduction

A

Control event rate - experimental event rate / control event rate

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6
Q

Number needed to treat

A

1 / absolute risk reduction

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7
Q

Brainstem death testing cranial nerves

A
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8
Q

Total resistance of resistors in parallel

A

1/ R total = 1/ R1 + 1/R2 + 1/R3 ….

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9
Q

Total resistance of resistors in series

A

R total = R1 + R2 + R3 ….

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10
Q

Venturi mask ratios

A

Always given as Air : Oxygen

Eg Venturi 3:1 is 3 air to 1 O2

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11
Q

Heat loss mechanisms order of significance

A

Really Cold Eggs Ruin Cake

Radiation
Convection
Evaporation
Respiration
Conduction

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12
Q

When is suxamethonium safe to use with burns patients

A

Up to 24-48 hours after burn

After that upregulation of extra-junctional receptors increases risk of hyperkalaemia

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13
Q

Renal clearance equation

A

Clearance = Urinary concentration x Urinary volume / Plasma concentration

Clearance ml/min
Concentrations mg/ml
Volume ml

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14
Q

Relevance of Volume of Distribution of a drug

A

Context sensitive half life

Affected by lipid solubility

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15
Q

Effect of pregnancy on PaCO2

A

Hyperventilation leads to reduced CO2

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16
Q

Physiological changes during pregnancy

A

Increased:
- Tidal volume
- Resp rate (mildly)
- SV
- HR (mildly)
- CO

Reduced:
- FRC

17
Q

Reynolds number equation

A

Re = pvd / n

p = Density of fluid
v = Velocity of fluid
d = Diameter of tube
n = Viscosity of fluid

18
Q

Reynolds number use

A

Estimate whether fluid flow through tube will be laminar or turbulent flow

Reynolds number < 2000 suggests likely to have laminar flow

19
Q

Upstroke of arterial line waveform indication

A

LV contractility

20
Q

Area under arterial line waveform indication

A

CO