Cardiac muscle Flashcards
what are two similarities between cardiac and smooth muscle?
both are striated and use the t-tubule mechanism (acting on sarcoplasmic reticulum)
what are the major differences between cardiac and smooth muscle?
the t-tubules store larger amounts of Ca++, cardiac muscle plateaus (longer contraction time), the strength of contraction depends on extracellular Ca++
the ability of cardiac muscle to depolarize and contract is ____________
intrinsic
what are some features of the S-A node?
almost no contractile muscle fibers, cell membrane is naturally leaky to Na+ and Ca++ ions – less (-) resting potential than other cardiac mm
what is end diastolic volume?
amount of blood left in heart at the end of diastole
what is end systolic volume?
volume of blood left after systole
what is ejection fraction?
the fraction of blood left in the heart after systole
where does the majority of the returning venous blood flow too?
directly from atria to ventricles
what is preload?
the amount of pressure on the ventricles when they are full
what is afterload?
peripheral pressure the ventricles have to pump against
the heart relies almost exclusively on __________ for energy metabolism. the energy primarily comes from _________
oxygen, oxidative metabolism of fatty acids
what is the extrinsic regulation of heart rate?
SNS by way of releasing norepinephrine to increase cardiac output
what type of message does the S-A node receive at rest?
inhibitory or “vagal tone”