Cardiac Medicine 🫀✅ Flashcards
Two patients who have silent MI
Elderly women and TII DM
Use of Killip Class
Used to stratify risk post MI
Initial therapy for all ACS
MONA (morphine, oxygen if <94, nitrates, 300mg aspirin)
List 5 meds all ACS survivors should be on, and 1 extras they may be on
Aspirin, another antiplatelet (p2y12 inhib), statin, beta blockers, ACEi’s. Maybe nitrate
Antiarrythmics and other meds causing prolonged QT
Amiodarone, sotalol, class 1a’s, macrolides (except clarithromycin), TCAs, antipsychotics, chloroquine
How to investigate and manage Torsades de Pointes
ECG. IV MgSO4
After ACS, when do we give dual vs triple therapy.
Dual for 12 mo, or Triple for 6mo (only if PCI was done)
What is in the dual and triple therapy (following ACS)
Dual: aspirin or cloppy (and) NOAC or VKA = 6mo
Triple: aspirin (and) Cloppy (and) VKA or NOAC = 3mo
NSTEMI or unstable angina identified.
Management ?
MONA, then do GRACE score to determine if PCI best or not
If GRACE score is </=3%. Do what?
Conservative management with Tiggy
GRACE score of >3% and patient hemodynamically stable, do what?
PCI within 72hours, and prasgruel or tiggy, and UFH
GRACE score >3% and patient hemodynamically unstable. mx?
PCI immediately. And prasgruel or tiggy, and UFH
If a patient has a GRACE score less than 4%, yet is hemodynamically unstable… what do we do? (Unlikely scenario)
Do immediate PCI (stability takes priority)
In NSTEMI/unstable angina, when is fondaparinux given?
If PCI not planned
STEM I usually presents with how many minutes of pain
20 or more minutes
In STEMI, we give dual antiplatelet therapy before PCI. Which dual antiplatelet drugs do we use (consider if patient is already taking oral anticoagulant)
If patient already taking oral anticoagulant give clopidogrel and aspirin. If patient not taking oral anticoagulant give prasgruel and aspirin
If a patient has a STEMI, what determines whether they have a PCI or not
If PCI can be done within 120 minutes Then most likely should be done
If cannot do PCI within 120 minutes, what is the alternative treatment for an STEMI
Fibrinolysis And antithrombin
Which anti-platelet should be given alongside PCI
Prasgruel with Pci
Following fibrinolysis, Which antiplatelet should be given
tiggy
Three Cardinal features of angina pectoralis
Constricting discomfort in the chest, precipitated by exertion, relieved by rest or GTN
Pass meds Answer for best investigation for angina (stable)
CT coronary angiography
Aside from normal angina medication all patients should be taking which two medications
Aspirin and statin
What medication can be taken to abort angina attacks
GTN
 Which two medications are considered first line for angina management
CCB and beta blocker
For angina if give CCB and beta blocker together, CCB must be which type
Dihydropyridine
In angina if a CCB is used as monotherapy, which CCB should be used
Verapamil or diltiazem
Cardio respiratory arrest – cardiac arrest. It’s usually down to which four rhythm disturbances
Ventricular fibrillation, pulseless ventricular tachycardia, pulseless electrical activity and asystole
Which investigations are important for cardiac arrest
Continuous cardiac monitoring. Then consider full blood count, electrolytes, ABG, x-ray, toxicology. Aside from ECG, this is all done after Mx
Management of cardiac arrest
ABCD, CPR (30 compressions then 2 breaths) for 5 cycles. Defib is shockable rhythm… recall
If defib doesn’t work for pulseless ventricular tachycardia/Vfib… can give what?
Amiodarone or Lidocaine
Best two invx for suspected endocarditis
Blood cultures and echo
Empirical antibiotics for endocarditis:
1. If native valve
2. If native valve but penicillin allergic
3. Severe sepsis
4. prosthetic valve
- Amoxicillin (+/-) low dose gentamicin
- Vancomycin and low dose gentamicin
- Vancomycin and low dose gentamicin
- Vancomycin and low dose gentamicin and rifampicin
Treatment of native valve staphylococcus endocarditis
Flucloxacillin (of vanco and rifampicin if penicillin allergic)
Prosthetic valve endocarditis due to staphylococcus treatment
Flucloxacillin and rifampicin and low dose gentamicin (vanco and rifampicin and low dose gentamicin if penicillin allergic)
Endocarditis due to fully sensitive strep (treatment)?
Benzylpenicillin (vanco and low dose gentamicin if allergic)
Endocarditis due to more resistant strep (treatment)
Benzylpenicillin (and a low dose gentamicin)
“Ben went to sRepton”
Monomorphic VT usually due to…
MI
Polymorphic VT usually due to what…
Prolonged QT
What do you see on an ECG in VT?
Wide QRS, regular rhythm, no p wave, and more than 100 bpm. And for >120ms
When do you cardiovert a patient with VT?
If patient has adverse signs, like SBP < 90, chest pain, HF
If a patient with VT presents, and has no ‘adverse signs’, how do you manage?
Antiarrythmics. Amiodarone IV is good, lidocaine ok (not if left Vent impaired), never Verapamil. If this doesn’t work, then can cardiovert
More than how many PVCs in a row = vent tachycardia
3
First Invx for VT and VF
ECG
Management for Vfib
Defib, and then an implantable cardioverter defibrillator (ICD)
Main risk factor for TdeP
Prologued QT
If suspect HF, do what Invx?
BNP
If BNP is high in suspected HF patient, do what to further Invx?
Trans thoracic echo
Management of acute HF (clue = like pulmonary edema)
IV furosemide, O2, vasodilators (unless hypotension), CPAP. And continue regular chronic HF meds
First line Invx for chronic HF patient
BNP
First line treatment (regime) for Chronic HF with preserved ejection fraction
ACEI and Beta Blocker (can add aldosterone antag. If still symptomatic)
Good add on for HF patients (black patients)
Hydralazine and nitrates
If cannot have Beta blocker in HF therapy… what can be used as a substitute
Ivabradine
If a patient with HF has widened QRS on ECG… how do you treat
Needs cardiac desynchronisation
HF patients Vx schedule
Annual influenza and one off pneumococcal
If intolerant to ACEI for HF management, use what?
ARB
If ACEi BB spirino are given for HF, and symptoms persist. Do what?
Replace ACEI with ARNI
If ACEi BB spirino are given for HF, and symptoms persist, whilst heart rate above 75. Do what?
Add ivabradine
Best investigation for pulmonary edema to find cause?
ECG (maybe)
investigations for pulmonary edema
Chest x ray (recall signs), ECG, oxygen, ABGs, BNP
Management of acute pulmonary edema
Oxygen with venturi, diuretics, morphine, nitrates
Considered high blood pressure
140/90
How to confirm diagnosis of hypertension
24 hour blood pressure monitor.
Why do we need to do and ECG in hypertension patients
Check for left ventricular hypertrophy or IHD.
Why should a urinalysis be done in patients with hypertension
To check for hypertensive renal disease
Stage 1 hypertension is?
> = 135/85
When do you treat stage 1 hypertension?
Treat if less than 80, and if there is target organ damage, CVD, renal disease etc
Most effective lifestyle change to decrease hypertension risks
DASH diet
What is stage 2 hypertension
> = 150/95
Do we always treat stage 2 hypertension
Yes
If a patient aged <40 presents with hypertension, what should be done/considered
Consider 2° hypertension and thus refer to specialist
Patient less than 55. Best drug for hypertension
ACEi
Patient over 55, best drug for hypertension
CCB
Black patient with hypertension. Best treatment?
CCB
Patient with T2 DM history. Best treatment
ACEi
If patient cannot tolerate ACEi cough, give???
ARB
4 first line treatments for hypertension
ACEi, ARB, thiazide, CCB
If patient on CCB, ACEi, thiazide (step 3), and K+ is less than 4.5. Can add what?
Low dose spirinolactone
If patient on CCB, ACEi, thiazide (step 3), and K+ is more than 4.5. Can add what?
Alpha or beta blocker
Black patient on CCB for hypertension, and needs step up. Give what?
ARB!
First degree heart block treatment?
NO treatment needed
PR interval has to be >? Seconds (>? Small squares) in first degree heart block
> 0.2 Seconds (>5 Small squares)
Complete heart block is often due to what? (Related to MI)
RCA occlusion
Best invx to confirm heart blocks
ECG of course
Indications for pacemaker in heart block
Usually, 2°M II, and 3°. Or if symptoms severe (symptoms of respiratory acidosis )
WPW syndrome risk for what arrhythmia
VF
WPW is a type of ______ tachycardia
AV re-entrant tachycardia
3 findings of WPW on ECG
Short PR, delta wave, axis deviation (opposite to the pathway involved)
Definitive treatment for WPW
Radiofrequency ablation
Medical therapy for WPW? (First line). Then if you cannot use the first line?
That’s sooooo WPW. Sotalol (don’t use if Afib present).
Amiodarone and flecainude second line
More than __ ms (or __ small squares) is a long QT
440 ms or 10 small squares
Long QT can cause what arrhythmias
Torsades, VT or VF
Jervell Lange nielsen vs Romano ward
Jervell has deafness. Both are due to mutated potassium channels causing LONG QT
Investigation for long QT
ECG, echo, holster monitor, genetics test, electrolytes
Sotolol in prolonged QT?
No! Can prolongue it more
Management and treatment for prolonged QT
Avoid QT prolong drugs, avoid strenuous excserize; and ICD for high risk case
When do we give anticoagulant in AF. First line anticoagulant for AF? Why?
If CHADS VASc score says so. DOAC (apix, Dabi, edox, rivarox.) don’t need INR monitoring.
If patient has AF, and is stable. What meds should be given
Beta blocker or CCB (rate control) and a DOAC if CHAD VASc suggests to
When is cardioversion needed in AF
If patient is unstable
If the patient needs anticoagulant for AF, and has a valve disease. 1st line?
Warfarin
CHA2DS2 VASc stands for? Used for?
CHF, HTN, age > 75, diabetic, stroke history, vascular disease, age 65-74, Sex.
To assess need for anticoagulant I’m AF patients
CHADS VASc of 1 or more in man means?
Needs anticoagulant
CHADS VASc of 2 or more in woman means?
Anticoagulate
If patient has AF, and want to cardiovert. Started less than 48 hours ago. Do what?
Cardiovert .
Don’t worry about anticoagulating them first
If patient has AF, and want to cardiovert. Over 48 hours has elapsed. What options do we have to manage
Either anticoagulate patient for 4 weeks, then cardiovert. Or do transesophageal echo to check for thrombi in the atrial appendage
Paroxysmal AF definition
AF that terminates itself and lasts less than 7 days