Cardiac Histology II Flashcards
The 3 tunics
Tunica intima
Tunica media
Tunica adventitia
Endothelium of tunica intima
Single layer of squamous cells.
Layers of the tunica intima
Endothelium Basal lamina Subendothelial cells (loose CT) w/ internal elastic membrane
Internal elastic membrane
Sheet-like layer of fenestrated elastic material in arteries and arterioles.
Tunica media
Thick in arteries.
Extends from internal elastic membrane to external elastic membrane (which separates tunica media from tunica adventitia).
Tunica adventitia
Merges w/ surrounding loose CT.
Thin in arteries and thick in veins.
Vasa vasorum
Vessels of tunica adventitia of large arteries and veins.
Supplies the vasculature itself.
Nervi vasorum
ANS input that controls contraction of vascular smooth muscle.
In large vessels, elastin forms:
Lamellae (sheets) between smooth muscle.
No fibroblasts.
Distribution of muscle and elastin in medium sized arteries (4):
More smooth muscle, less elastin.
The internal elastic membrane becomes very apparent.
External elastic membrane also apparent.
Thick tunic adventitia.
Small arteries have how many layers of SM?
Up to 8
Arterioles have how many layers of SM?
1-2 layers and internal elastic membrane may or may not be present.
Pericytes
Perivascular contractile cells w/ branching cytoplasmic processes.
Controlled by NO.
Promotes stability of capillaries and postcapillary venules
Continuous capillaries
Have complete endothelial cells and pericytes.
Found in many places in the body. Most common.
Fenestrated capillaries
Have fenestrated endothelial cells.
Found in sites of fluid/metabolite absorption (gallbladder, kidneys).
Discontinuous/sinusoidal capillaries
Discontinuous basal lamina and fenestrations.
Found in spleen, liver, bone marrow.
Metarterioles
First branch off of arteriole supplying tissues.
True capillaries
Branch from metarteriole.
No smooth muscle.
May or may not have pericytes.
Thoroughfare channel
Distal end of metarteriole.
No smooth muscle.
Connects arterioles to venules.
Diameters of veins (small, medium, large)
Less than 1 mm
10 mm or less
Greater than 10 mm
Veins vs. arteries
Veins have thinner walls. The lumen is larger, but can be collapsed.
Postcapillary venules
Drain capillaries , no true tunica media.
Muscular venules
Have 1-2 layers of SM in tunica media.
Thin tunica advventitia.
Small veins
Have 3 tunics.
Thicker tunica adventitia.
Tunica media has 2-3 layers.
Hierarchy of veins (5)
Postcapillary venules -> muscular venules -> small vein -> medium vein -> large vein
Medium veins
Thicker tunica media and adventitia.
Contains valves.
Large veins
Very thick tunica adventitia.
Tunia media and tunica intima both thin.
Has circumferentially arranged SM cells.
Lymphatic capillaries
Overlapping endothlial cells make valves.
Has incomplete basal lamina which increases permeability.
Anchoring filaments
Hold the openings open in the endothelial cells.
Lymphatic vessels have:
All tunics and valves.