Cardiac Diagnostics

Question 1

The higher the troponin the _______ the outcome.

Answer 1

Worse

Question 2

Toponin rises within ___ to ___ hours after cardiac insult.

Answer 2

2 - 3 hours

it may stay elevated for 10 days to 2 weeks after

Question 3

Which medication can cause a rise in troponin?

Answer 3

Thrombolytics

Reffered to as “wash out”

Question 4

CK-MM

Answer 4

Creatine kinase in skeletal muscle and heart damage

Question 5

CK-MB

Answer 5

Creatine kinase in heart damage
Concentrated in the myocardium
Limited diagnostic value alone

Question 6

CK-BB

Answer 6

Creatine kinase in brain damage

Question 7

CK-MB/CK relative index values

Answer 7

Less than 3 = skeletal muscle source

Ratio greater than 5 = cardiac source

Question 8

Lab tests for CV risk assesment

Answer 8

Lipid profile
hs-CRP
Homocystine

Question 9

CRP

Answer 9

Measures general levels in inflammation in the body

Elevated in infxn, chronic dz, surgery

Question 10

hs CRP

Answer 10

High-sensitivity CRP
elevated = 2-3x the risk of MI, stroke, PAD
Major use in primary prevention

Question 11

Homocystine

Answer 11

Amino acid
acquired mostly from meat protein
Elevated levels are related to low levels of B6, 12 and folate.
Elevated levels related to CVD

Question 12

BNP

Answer 12

Brain Naturiuretic Peptide
Produced by atrium and ventricles in response to an increase on volume and pressure.
Stimulates release of Atrial NP.
May be helpful to determine between CHF and lung disease

Question 13

AST

Answer 13

Aspartate Transaminase
Enzyme released in injury of heart and liver tissue
Used to evaluate liver disease

Question 14

LDH

Answer 14

Lactate Dehydrogenase
Elevated in hemolytic anemia
Not so useful for heart dz (better tests)

Question 15

Holter monitor

Answer 15

Heart monitor worn for 24 hrs

Question 16

Event monitor

Answer 16

Worn for a month
Patient triggers monitor to record during event
New devices can detect arrhythmias