Cardiac Cycle Flashcards
What is the cardiac cycle?
Series of consecutive contractions and relaxations of the heart, to ensure a continuous flow of blood & circulation around the body.
What is Ventricular diastole?
Diastole: Ventricular relaxation during which the ventricles fill with blood. Preload attributed to isometric contractions and stretching of an intracellular network of the cardiomyocyte.
How many phases are present during diastole?
4 phases
How many phases are present during systole?
3 phases
What is systole?
Systole: Ventricle contraction generates pressure, ejecting blood into the arteries for both pulmonary and systemic circulation.
What is an isovolumetric contraction?
Pressure builds up in ventricles, however ventricles do not expel blood until pressure overcomes afterload.
At what point does ventricular ejection proceed?
Pressure generated during isovolumetric contractions exceeds afterload
What phases occur after isovolumetric contraction?
Ventricular ejection and relaxation
What enables ventricular filling?
Passive filling of blood through pressure gradient into ventricle from atria. Atrial contraction (Systole)
What is End Diastolic volume (EDV)?
Volume of ventricles prior to systole
What is End-systolic volume (ESV)?
Volume in the ventricles after slow ejection (end stage of systole)
What is stroke volume?
The volume of blood expelled from the left ventricle during ventricular systole
EDV-ESV
What is the ejection fraction (EF)?
Proportion of the end diastolic volume that is ejected into systemic circulation during systole.
SV/EDV
What does EF illustrate?
The contractility of the heart
What is the normal ejection fraction?
52-72%
What is the typical EF for patients with heart failure?
35%
How does blood passively fill the ventricles?
Prior to atrial systole, the blood passively flows through the atrioventricular orifice through the mitral and tricuspid valve
What is the valve between the right atrium and right ventricle?
Tricuspid Valve
What is the left atrioventricular valve?
Mitral valve
What happens to the pressure during atrial filling (Atrial diastole)?
Pressure of atrium increases
P of atrium > p ventricle
How is atrial contraction stimulated?
Waves of excitation from the sinoatrial node
How is atrial systole depicted on the ECG?
P wave
What is the abnormal heart sound due to valve incompetency?
S4
What is S4?
Turbulent blood flow through dysfunctional valve closure.
What causes s4?
Pulmonary embolism,
Congestive heart failure
Tricuspid incompetennce
Which valves are closed during isovolumetric contraction?
Atrioventricular and semi lunar valves are closed
pressure is accumulating
Describe the pressure gradient during an isovolumetric contraction?
Ventricular pressure > atrial pressure
Describe the interval of the isovolumetric contraction?
Interval between the AV valves closing, and the semi-lunar valves opening