Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

CLS > Carcinogens and Metaplasia > Flashcards

Carcinogens and Metaplasia Flashcards

1
Q

Polycyclic hydrocarbons effect

A

Carcinogenic
Founds in tars, i.e. cigarette smoke
Cause lung canceer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Aromatic Amines; carcinogenic effect

A

Through industrial exposure
Converted to active ingredients in liver
- Become concentrated by excretion in the urine, main effect on urothelium causing cancers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Nitrosamines; carcinogenic effect

A

cause cancer in stomach and GI tract

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Alkylating agents; carcinogenic effect

A

Can bind to DNA and are directly mutagenic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Examples of hormones promoting tumour growth

A
  • Oestrogens stimulate proliferation of breast & endometrial tissue; can be treated by anti-oestrogen drugs
  • Carcinoma of prostate can be treated by removal of testosterone stimulation by orchidectomy or oestrogenic drugs
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

A physical carcinogen

A

Asbestos

Inhaled fibres are potent cause of neoplasia in lung and pleura

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Neoplasms related to EBV

A

Burkitt’s Lymphoma, Naspharyngeal, B-cell lymphomas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Neoplasms related to HBV

A

Hepatocellular carcinoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Neoplasms related to HPV

A

Cervical cancer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Neoplasms related to HTLV-1

A

T-cell leukaemia/lymphoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Neoplasms related to HHV-8

A

Karposi’s Sarcoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Tumour caused by Li-Fraumeni

A

Breast cancer and sarcomas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Tumour caused by Polyposis coli

A

Adenomate and carcinoma of colon

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Tumour caused by familial retinoblastoma

A

Malignant tumour of retina

How well did you know this?
1
Not at all
2
3
4
5
Perfectly

CLS (20 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions