Carbohydrate Metabolism II

Question 1

occurs in the mitochondria; main function of the cycle is the oxidation of acetyl-CoA to CO2 and H2O, in addition produces NADH and FADH2``

Answer 1

citric acid cycle/ Krebs cycle/ TCA cycle

Question 2

acetyl-CoA and oxaloacetate combine through intermediate steps to form citrate; catalyzed by citrate synthase

Answer 2

Citrate Formation in CAC

Question 3

achiral citrate is isomerized to one of four possible isomers of isocitrate

Answer 3

Citrate isomerized to isocitrate

Question 4

isocitrate oxidized to oxalosuccinate by isocitrate dehydrogenase then decarboxylated to produce

Answer 4

alpha- ketoglutarate and CO2

Question 5

rate limiting enzyme for CAC

Answer 5

isocitrate dehydrogenase

Question 6

only step of the CAC that doesn’t take place in the mitochondrial matrix but occurs on the inner membrane

Answer 6

Fumarate formation

Question 7

an electrochemical proton gradient generated by the complexes of the ETC

Answer 7

proton-motive force