Carbohydrate 1 Flashcards

1
Q

How are carbohydrates absorbed ?

A

Carbohydrate in the lumen, Transferrers through the microvilli into intestinal cells. It’s then absorbed through into the capillaries, then into hepatic portal vein to the liver.

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2
Q

Goals or pre-exercise feeding ?

A

Replenish liver glycogen and encourage some glycogen synthesis

promote extra glycogen synthesis
Increase CHO oxidation during exercise at expense of fat metabolism.

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3
Q

Glucose muscle uptake ?

A

Glucose in blood travels to interstitial space
GLUT4 transferring in myocyte
Transferred into G-6-P by hexokinase
Then into glycolysis or glycogenesis

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4
Q

Support for sleep low training?

A

Increases AMPK and P38 for mitochondrial biogenesis.

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5
Q

With fructose derived trioses what are the percentages of what happens to this ?

A

50% gluconeogenesis to glucose
15-25% gluconeogenesis to glycogen
25% to pyruvate or lactate

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6
Q

Some methods to train low ?

A
Low CHO diet
2x daily training
Long session
Sleep low
No carb recovery
Training after overnight fast.
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7
Q

When fructose is transported to the liver what happens when it arrives here ?

A

Converted to fructose 1-p
then to triose-p

From here it can either be converted to glucose 6-p to be stored or used as energy

Or immediate to pyruvate to aerobically make energy or to lactate.

if lactate can become fatty acids and release triglycerides.

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8
Q

Why does exercise increase glucose uptake more than insulin?

A

Because of the much greater flow of blood allows increased glucose transport to the muscles.

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9
Q

Yes vs No considerations for CHO loading.

When to and when not to ?

A

Should consider.

  • High glycogen demand
  • Longer than 90 mins continuous
  • If diet is low CHO
  • No medical reasons not to.

Should not considerer/ non necessary.

  • Short / Under 80mins
  • Adversely effected by weight gain. 1g glycogen has 3gram water.
  • Hi Carb diet already 8-9g/kg/d
  • Unstable diabetes
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10
Q

Burke’s recommendation for pre exercise meal ?

A

> 60mins
1.4g/kg
1-4 hours before exercise ?

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11
Q

Two pathways of carbohydrate usage ?

A

Glycolysis

Oxidative Metabolism

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12
Q

What are the four sources of carbohydrate and some examples that fit in each ?

A

Monosaccharides - Single sugar unit
Glucose, fructose, galactose.

Disaccharides - Two sugar units
Sucrose (glucose + fructose) , Maltose (2x glucose), Lactose (Glucose + Galactose)

Oligosaccharide - 8-12 glucose molecules
Maltodextrin

Polysaccharides - Branched long chain glucose molecules.
Amylopectin (starch) , Amylose

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13
Q

What is the transport mechanism for glucose to be transported form the intestinal lumen to the blood stream ?

A

Via Sodium link transporter 1 (SGLT1) into the intestinal cells, Then carried by GLUT2 to the blood stream.

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14
Q

What are the General carbohydrate requirements for differing training loads as suggested by Burke et al., 2011?

A

Light - Low intensity or skill based activity - 3-5g/kg/d

Moderate - 1 hour per day - 5-7g/kg/d

High - endurance program/ 1-3 hours day mod/ high intensity - 7-10g/kg/d

Very High - 4-5 hours mod/high - 10-12g/kg/d

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15
Q

Estimated g of carb and calories to this stored in an 80kg man ?

A

0.52kg

2000kcal

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16
Q

What is one benefit of a low CHO diet for endurance adaptation?

A

Increases AMPK and P38 activation.

This stimulates PCc1a and P53 resulting in mitochondrial biogenisis.