Carbapenemicos y Monobactamicos Flashcards

1
Q

Mecanismo de accion de los carbapenemicos

A

Inhibe la sintesis de peptidoglucano

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2
Q

Mencione los carbapenemicos

A

Imipenem, Ertapenem, Meropenem y Doripenem

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3
Q

Cobertura de los carbapenemicos

A

Cocos gram +: Strep, Staph, Enterococo
Bacilos gram - aerobios: PSEUDOMONAS
ANAEROBIOS

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4
Q

Via de administracion de los carbapenemicos

A

EV. El Ertapenem puede darse intramuscular tambien. El ertapenem se da una vez al día

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5
Q

Via de eliminacion de los carbapenemicos

A

Renal, excepto el ertapenem (Hepatica)

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6
Q

Que sucede con el imipenem?

A

Es inactivado por la dihidropeptidasa renal, por lo que debe ser administrado con cilastatina, para inhibir esta enzima

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7
Q

Cual es el carbapenemico que disminuye el umbral convulsivo?

A

Imipenem

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8
Q

Cual es el carbapenemico mas activo contra bacilos gram -?

A

Meropenem, por lo tanto es el de eleccion en infecciones intraabdominales severas

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9
Q

Contraindicaciones de los carbapenemicos

A

Neumonía (Solo ertapenem y doripenem)

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10
Q

Indicaciones de los carbapenemicos

A

Infecciones intraabdominales severas
Peritonitis 3ria + vancomicina y fluconazol
Neumonia, excepto doripenem

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11
Q

Mecanismo de accion de los monobactamicos

A

Inhiben la sintesis de peptidoglucano

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12
Q

Nombre un monobactamico

A

Aztreonam

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13
Q

Cobertura de los monobactamicos

A

Bacilos gram - multirresistentes

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14
Q

Indicaciones de los monobactamicos

A

Alergicos a penicilinas

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15
Q

Efectos adversos de los monobactamicos

A

Diarrea y vomitos

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