Carbamazepine

Question 1

Pre-drug work up for carbamazepine?

Answer 1

LFTs, CBC with diff, electrolytes especially sodium, severe rash or Steven Johnson, EKG especially if greater than 40 years old

Question 2

Drug interactions with oral contraceptive pills and carbamazepine?

Answer 2

Increase metabolism of oral contraceptive pills. Need higher dose or alternative methods

Question 3

Tegretol and MAO inhibitors interactions?

Answer 3

MAOI are contraindicated with Tegretol

Question 4

Tegretol use with clozapine interaction?

Answer 4

Concurrent use of clozapine and strong CYP3A4 inducers may result in reduced clozapine exposure and decreased efficacy

Question 5

Info Tegretol

Answer 5

CYP 3A4 substrate auto inducer

Question 6

How Long do you have to wait to check blood levels for tegretol?

Answer 6

4 days to steady state

Question 7

What is Carbamazepine used for?

Answer 7

Bipolar, acute mania, epilepsy, neuralgia