cancer therapy Flashcards

1
Q

what are the steps prior to treatment for cancer?

A
Self detection/referral
Diagnosis
◦ Disease site
◦ Staging
◦ Histology/genetics
Surgery/radiotherapy/chemotherapy or supportive care
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2
Q

when it comes to treatment decision what are the intent of it ?

A
  • curavtive
  • neoadjuvant (surgery before to reduce size)
  • palliative
  • monotherapy or combination
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3
Q

what ar som eimportant considerations for treatment?

A
  • patient specific dosing -body surface and kg, flat odsing

- patient, performance status, age, previous treatment

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4
Q

what is combination therapy?

A
  • using drugs with different mechanisms of action
  • targets mutiple pathways
  • reduce toxicity
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5
Q

why may drug resistance occur?

A
  • Mutation of targets
  • Increased metabolism = deactivation
  • Decreased drug influx–increased drug efflux
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6
Q

what is hormone therapy?

A

removing the hormone that feeds the tumor like oestrogen in the breats and ovaries and progestron in the prostate
-can also use drugs to block hormone receptors

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