cancer therapy

Question 1

what are the steps prior to treatment for cancer?

Answer 1

Self detection/referral
Diagnosis
◦ Disease site
◦ Staging
◦ Histology/genetics
Surgery/radiotherapy/chemotherapy or supportive care

Question 2

when it comes to treatment decision what are the intent of it ?

Answer 2

• curavtive
• neoadjuvant (surgery before to reduce size)
• palliative
• monotherapy or combination

Question 3

what ar som eimportant considerations for treatment?

Answer 3

• patient specific dosing -body surface and kg, flat odsing

- patient, performance status, age, previous treatment

Question 4

what is combination therapy?

Answer 4

• using drugs with different mechanisms of action
• targets mutiple pathways
• reduce toxicity

Question 5

why may drug resistance occur?

Answer 5

• Mutation of targets
• Increased metabolism = deactivation
• Decreased drug influx–increased drug efflux

Question 6

what is hormone therapy?

Answer 6

removing the hormone that feeds the tumor like oestrogen in the breats and ovaries and progestron in the prostate
-can also use drugs to block hormone receptors