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Pharmacology > Cancer Chemotherapy > Flashcards

Cancer Chemotherapy Flashcards

1
Q

Alkylating Agents

A 
Cyclophosphamide
Ifosfamide
Busulfan
Mechlorethamine
Cisplatin
Carboplatin
Oxaliplatin
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2
Q

Antitumor antibiotics

A

Anthracyclines
Podophyllotoxin Derivatives
Campthotheca Derivatives

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3
Q

Anthracyclines

A

Doxorubicin
Daunorubicin
Idarubicin
Epirubicin

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4
Q 
Podophyllotoxin derivatives
(Podophyllum peltatum)
A

Etoposide

Teniposide

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5
Q

Camptotheca derivatives

A

Irinotecan

Topotecan

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6
Q

Antimetabolites

A

Folic Acid derivatives
• Methotrexate
• Premetrexed

Purine/Pyrimidine Analogs
• 5 - FU

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7
Q

Antimitotics

A

Taxanes
• Paclitaxel
• Docetaxel
• Cabazitaxel

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8
Q

Vincas

Catharanthus roseus

A

Vincristine
Vinblastine
Vinorelbine
Vindeline

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9
Q

– MOA: Inhibition of dihydrofolate reductase

A

Antimetabolites

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10
Q

– MOA: Inhibits VEGF-R

A

Bevacizumab

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11
Q

– MOA: Inhibits EGF-R

A

Cetuximab

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12
Q

– MOA: Inhibits HER2/ neu R

A

Trastizumab

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Pharmacology (21 decks)

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