Cancer Flashcards
thrombocytopenia that cause purupura, petechial and bleeding
- short stature
- café au lait spots
- skeletal malformation like the absence of a thumb and radius
aplastic anemia
What does the CBC of aplastic anemia look like?
progressive pancytopenia
progressive pancytopenia
aplastic anemia
what is the difference between alpha and beta thalassemia?
beta: no response to iron therapy
Anemia with elevated reticulocyte count and maybe jaundice +/-heptosplenomeagly
sickle cell anemia
What is dactylitis and what is it associated with?
sausage digits! sickle cell anemia
With iron deficiency anemia, at what age are you more concerned about chronic blood loss?
older than 2 years old, if the patient is younger than that think poor dietary intake
Can cause neonatal hyperbilirubinemia
G6PD deficiency
Have episodic hemolysis at times of oxidant stress
G6PD deficiency
What type of cells are associated with G6PD?
bite cells or blister cells; may see Heinz bodies in stains
How do you prevent the episodic hemolysis associated with G6DP?
avoid fava beans, avoid infections and avoid drugs associated with hemolysis
Otherwise healthy child, markedly decreased platelet count, petechiae, eechymoses
idiopathic thrombocytopenic purpura
This is the most common bleeding disorder in childhood
acute ITP; often following an infection or virus
The goal of treatment is to raise factor VII activity
hemophilia
Easy bruising, epistaxis, menorrhagia, prolonged PFA, reduced activity of vWF
von willebrand disease
