CAMTASIA: Spermatogenesis, Sertoli Cell, Feedback Pathways of Spermatogenesis

Question 1

Where does spermatogenesis occur?

Answer 1

The wall of the seminiferous tubules

Question 2

Where do progenitor cells exist?

Answer 2

The boundary of the seminiferous tubules

Question 3

T/F All progenitor cell clones move on to form sperm

Answer 3

FALSE. Some stay and become progenitor cells themselves

Question 4

The primary spermatocyte is protected from the interstitium by a ____

Answer 4

Tight junction

Question 5

A primary spermatocyte undergoes meiosis I to form ____

Answer 5

2 spermatocytes

Question 6

The secondary spermatocytes undergo meiosis II to form ____

Answer 6

2 spermatids

Question 7

The primary spermatocyte ultimately forms ____ spermatids

Answer 7

4

Question 8

____ cells bath the spermatids in testosterone and nourish them to become little tadpoles of love

Answer 8

Sertoli

Question 9

When it comes to male steroid hormones, the hypothalamus releases ____ to stimulate the release of ____ and ____ from the ____ pituitary.

Answer 9

GnRH, LH, FSH, anterior

Question 10

LH is responsible for stimulating the ____ cells in the testes

Answer 10

Leydig

Question 11

FSH is responsible for stimulating the ____ cells in the testes

Answer 11

Sertoli

Question 12

____ cells synthesize testosterone and release it into the interstitium to diffuse across to the sertoli cells.

Answer 12

Leydig

Question 13

Sertoli cells can release an antigen binding protein that keeps ____ local

Answer 13

Testosterone

Question 14

T/F Testosterone is used in feedback to the anterior pituitary and hypothalamus to ONLY inhibit GnRH and LH but not FSH.

Answer 14

True

Question 15

Sertoli cells also release ____ which go back to the ____ to inhibit the release of ____

Answer 15

Inhibin, anterior pituitary, FSH

Question 16

____ feedback inhibits the release of LH from the anterior pituitary and ____ from the hypothalamus and ____ feedback inhibits the release of only FSH from the anterior pituitary.

Answer 16

Testosterone, GnRH, inhibin

Question 17

What is the most potent form of testosterone?

Answer 17

Dihydrotestosterone

Question 18

____ is the catalyst for testosterone to become dihydrotestosterone

Answer 18

5 alpha reductase

Question 19

The androgen binding protein secreted from the sartoli cells binds up to ____% of ____

Answer 19

98%, testosterone

Question 20

What are the 8 functions of sartoli cells?

Answer 20

Nurture sperm, move sperm, antigen binding protein, quality control of sperm, inhibin production for feedback, creates the tight junction barrier

Question 21

In a female, the equivalent of sartoli cells are ____

Answer 21

Granulosal cells

Question 22

In a female, the equivalent of leydig cells are ____

Answer 22

Thecal cells

Question 23

Though testosterone has only a ____ feedback effect on the anterior pituitary, estrogen can ____ or ____ influence the anterior pituitary depending on the levels.

Answer 23

Negative, positive (low levels), negative

Question 24

____ cells secrete testosterone and progesterone

Answer 24

Thecal cells

Question 25

In which phase of development is LH higher than FSH?

Answer 25

Post puberty

Question 26

On day ____ of the 28 day menses, ovulation occurs.

Answer 26

14

Question 27

In a woman, ____ cells make inhibin and convert testosterone to estrodile by secreting ____

Answer 27

Granulosal cells, aromatase