CAMTASIA: Digestion of Carbohydrates, Fats, Proteins, Calcium, Iron Flashcards

1
Q

____ amylase first begins to break down nutrients in the ____

A

Salivary, stomach

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2
Q

____ amylase is released into the duodenum to break down complex starches into ____

A

Pancreatic, disaccharides

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3
Q

____, ____, ____ are found in the brush borders of the duodenum and break down maltose, sucrose, and lactose respectively.

A

Maltase, sucrase, lactase

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4
Q

Maltose is broken down to ____

A

Glucose

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5
Q

Sucrose is broken down to ____

A

Glucose, fructose

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6
Q

Lactose is broken down to ____

A

Glucose, galactose

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7
Q

T/F The breakdown of the monomers, glucose, fructose, and galactose happens far from their absorptive surfaces.

A

FALSE. The hydrolytic enzymes that break them down are found within the wall where the absorption takes place.

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8
Q

T/F You need a transporter to move the monomers into the cell, but they can move down their concentration gradient when they move into the interstitium

A

TRUE

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9
Q

The venus return of the carbohydrate nutrients int the GI tract takes the nutrients directly to the ____

A

Liver

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10
Q

The digestion of fats is done ONLY by ____

A

Pancreatic lipase

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11
Q

Most fats as they reach the intestines are in the form of ____

A

Triglycerides

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12
Q

Pancreatic enzymes will cleave triglycerides into ____ and ____

A

Fatty acids, monoglycerides.

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13
Q

T/F Fats need a transporter to move into the cell.

A

FALSE. They are lipid soluble.

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14
Q

When do monoglycerides and fatty acids turn back into triglycerides?

A

When they are moved into the cell.

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15
Q

After triglycerides are formed in the cell, they are incorporated into a ____ when they join other fat soluble substance such as ____, ____, ____

A

Chylomicron, cholesterol, fat soluble vitamins, phospholipids.

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16
Q

After the chylomicrons are exocytosed into the interstitium, most are picked up by the ____ with only some being taken up by the ____

A

Lymphatic system, portal vein to the liver

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17
Q

Proteins coming into the stomach are in the form of ____

A

Long polypeptides

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18
Q

T/F Proteins are mechanically, chemically, and enzymatically broken down in the stomach by the motion of the muscle walls (mechanical) as well as hydrochloric acid (chemical) as well as pepsin (enzymatic)

A

TRUE

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19
Q

____ turns to pepsin in the acidic environment of the stomach.

A

Pepsinogen

20
Q

____ is important for the reabsorption of vitamin B12

A

Intrinsic factor

21
Q

Proteolytic enzymes are released from the pancreas in the duodenum in the form of ____

A

Zymogens

22
Q

____ cleaves to ____ and then is responsible for converting all other ____ to active enzymes so they can break down the proteins.

A

Trypsinogen, trypsin, zymogens

23
Q

Proteins are broken down into ____ or ____ or ____

A

individual amino acids, dipeptides, tripeptides

24
Q

Amino acids do/do not need a cotransporter (Na+) to enter the epithelial cell.

A

DO.

25
Q

Amino acids move into the interstitium by means of ____

A

Facilitated transport

26
Q

Once in the interstitium, amino acids are either taken up into the ____ system or are taken into the ____

A

Lymph, portal vein

27
Q

Di/tripeptides enter the epithelial cell via a ____ and are then broken down into the ____ once in the cell.

A

Hydrogen symporter, amino acids

28
Q

Calcium absorption is regulated by the intracellular synthesis of ____, a calcium binding protein.

A

Calbindin

29
Q

Iron absorption is regulated by the intracellular synthesis of ____, a ferrous (iron) binding protein.

A

Ferritin

30
Q

More calbindin means ____ calcium will be absorbed.

A

More

31
Q

More ferritin means that ____ iron will be absorbed.

A

Less

32
Q

Calcium absorption is under ____ control

A

Hormone

33
Q

Iron absorption is controlled by ____

A

Plasma levels

34
Q

T/F Calcium enters the cell already bound to calbindin.

A

FALSE. Once it enters, it binds to calbindin.

35
Q

Calcium leaves the cell via a ____ or ____

A

Calcium ATPase pump, Na+/Ca2+ exchanger

36
Q

Active ____ increases absorption of calcium by increasing ____ and ____ activity.

A

Vitamin D, calbindin, calcium ATPas pump

37
Q

Once calcium is bound to calbindin within the cell, it is transported to what membrane?

A

Basolateral

38
Q

Calcium enters the cell via ____

A

Diffusion. It is gradient based.

39
Q

We only absorb about ____% of the iron that is ingested.

A

10%

40
Q

An increase in plasma iron leads to an ____ in ferritin synthesis leading to an ____ in binding and a ____ in transport across the membrane into the vasculature and thus a ____ of iron in the blood.

A

Increase, increase, decrease, decrease

41
Q

There are ____ ways to transport iron into the epithelial cell.

A
  1. Ferrous and Ferric forms.
42
Q

A higher concentration of ferritin means ____ iron will be available to be transported out.

A

Less

43
Q

_____ and ____ stimulates parietal cells to secrete HCl and intrinsic factor

A

Gastrin, ACH

44
Q

____ potentiates the actions of gastrin and ACH

A

Histamine

45
Q

____ and ____ inhibits the parietal cells

A

Prostaglandins, somatostatin