Caliciviridae

Question 1

Are caliciviruses enveloped or non enveloped?

Answer 1

non-enveloped

Question 2

To what genus does feline calicivirus belong?

Answer 2

Vesivirus

Question 3

T/F: the genomic RNA of caliciviridae is not infectious

Answer 3

FALSE

linear, single stranded, positive sense RNA

Question 4

Where in the cell do caliciviruses replicate?

Answer 4

Cytoplasm

Question 5

What clinical signs do you see in a cat with classical calicivirus?

Answer 5

Oral and upper respiratory infection (tongue ulcers, chronic ulcerative proliferation of gums, rhinitis)

sometimes limping/lameness (synovitis)

Question 6

What are the pathological processes of FCV-VSD (virulent systemic disease)?

Answer 6

Much higher mortality than classical calicivirus (~50%)

Ulcerations of tongue, gingiva, nasal cavity, and haired skin. Sloughing of paw pads, pneumonia, necrosis of the liver, spleen, and pancreas

Clinical: fever, facial edema, crusted lesions, ulcers and alopecia, jaundice, respiratory distress

Question 7

T/F: the feline calicivirus vaccine available has been effective in protecting against the virulent systemic strain

Answer 7

FALSE

Question 8

Is the clinical disease produced by Vesicular Exanthema of Swine (VES) distinguishable from Foot and Mouth dz, vesicular stomatitis , or swine vesicular dz

Answer 8

NO. These dz are all indistinguishable via clinical presentation

Question 9

How does a pig get VES?

Answer 9

Direct contact or eating infected pork

Question 10

How often are there outbreaks of vesicular exanthema of swine in the united states?

Answer 10

There aren’t!! it has been eradicated from the united states

Reportable

Question 11

Clinical signs of VES?

Answer 11

fever and formation of vesicles on the snout, oral mucosa, soles of the feet/coronary band - causing lameness

Question 12

What are the clinical signs seen in sea lions with San Miguel Sea Lion virus?

Answer 12

Formation of vesicles in oral cavity and on flippers