Calculations and Drug Information in Pediatrics Flashcards

1
Q

Peds dosing is _______-based

A

weight

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2
Q

When calculating peds doses, what should you keep in mind? (in terms of the maximum dose)

A

Adult dose- it’s the max peds dose!

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3
Q

Gestational age definition

A

from conception, “how far along in the pregnancy”

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4
Q

Post-natal age definition

A

Chronological age, time in days/weeks/months/etc. since the birthday

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5
Q

Post-menstrual age definition

A

GA + PNA

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6
Q

Neonate age range

A

Birth-28 days

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7
Q

Infant age range

A

30 days-1 year old

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8
Q

If a patient is preterm… (age)

A

PMA/corrected up to ~44 weeks

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9
Q

Child age range

A

1-12 years old

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10
Q

Adolescent age range

A

12-18 years old

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11
Q

LexiComp: dosing for peds

A

Recommendations stratified by age, weight, etc.
Take note of max mg/dose or mg/day recommendation
Find right indication
Look at the right route

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12
Q

LexiComp: preparation for administration

A

Provides information such as concentrations and appropriate diluents for reconstitution/dilution of parenteral medications
Provides instructions for enteral preparation- powder packets, dissolving tablets

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13
Q

LexiComp: administration

A

Contains special instructions related to administration with food and missed doses
Recommendations for food or beverages allowable for mixing
Parenteral: infusion info- rate of infusion

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14
Q

LexiComp: ADEs

A

ADEs that have been observed in clinical trials/post-marketing
May be organized by body/organ systems
May or may not be specific to patient age, provide % incidence, etc.

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15
Q

LexiComp: extemporaneous compounding

A

Provided published reference for recommendations related to compounding into PO solution/suspension from tablets or capsules

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16
Q

LexiComp: PK/MoA

A

May be necessary for answering DI questions related to how quickly a med works, onset of action, etc.
½-life can assist with understanding dosing intervals- may be age-specific if available
Bioavailability: can assist with parenteral to enteral conversations if not otherwise stated

17
Q

LexiComp: dosage forms, US and Canada

A

Available products on the market
Brand names and generic available
Assist in determining if commercially available PO solution/suspension is available for pediatric use
Helps to determine timed-release products availability