Calcium Channel Blockers

Question 1

What is dihydropyridines?

Answer 1

CCB-block entry for Ca2+ by voltage dependent calcium channels

selective dilation of peripheral and coronary arterioles—moderate depressant action on the heart

lowers afterload w/ no effect on preload

don’t give for congestive heart failure

Question 2

What type of formulation should dihydropyridines be given as

Answer 2

rapid and slow release forumulation