C19 Flashcards
1
Q
Urinary AntiSeptics?
examples
A
Nitrofurantoin
Phosphomycine
2
Q
What are urinary antiseptics?
A
oral drugs that are rapidly excreted into the urine and act there to suppress bacteriuria
3
Q
about Nitrofurantoin?
A
- against many urinary tract pathogens (but not Proteus or Pseudomonas)
- Resistance emerges slowly
- active orally
- excreted in the urine (filtration and secretion)
- avoided in Renal dysfunction
toxicity:
1. G.I irritation
2. skin rashes
3. pulmonary infiltrates
4. neuropathies
5. hemolysis (G6PD deficiency)