▪️C1.3 -cell Memebranes and transport Flashcards
Why are phospholipids a important component of the cell surface membrane?
- they can form bilayers
- inner layer of phospholipids has its hydrophilic head pointing in towards the cell, interacting with the water in cytoplasm
- outer layer has its hydrophilic head pointing outwards, interacting with the water surrounding the cell
- hydrophobic tails point towards each other, to the centre membrane
- phospholipid component of a membrane allows lipid soluble molecules across but not water soluble molecules
Where are proteins in a cell membrane?
Name the 2 forms of protein present
Scattered throughout the phospholipid Bilayer of the membrane embedded as either extrinsic or intrinsic proteins
Describe extrinsic proteins and their purpose
On the surface of the bilayer.
Provide structural support
Form recognition sites by identifying cells and receptor sites for hormone attachment
Describe intrinsic proteins and their purpose
Extended across both layers of the phospholipid bilayer
Includes carrier and channel proteins
What do carrier proteins (intrinsic proteins) do?
They transport water soluble substances across the cell membranes
What do channel proteins (intrinsic proteins) do?
Allow active transport of ions across the membrane through forming channels
Why is the fluid mosaic structure called the fluid mosaic structure?
- the individual phospholipid molecules can move within a layer relative to one another (fluid)
- the proteins embedded into the bilayer vary shape and size and pattern (mosaic) lol
Where in the cell membrane is cholesterol found? What is it’s purpose?
In the membranes of animal cells, between the phospholipid molecules, making the membrane more rigid and stable
Where in the cell membrane are glycoproteins and glycolipids found?
In the outer layer of the membrane.
What is the outer layer around the cell membrane called? What is it’s role?
The glycocalyx
The molecules in the glycocalyx have roles as hormone receptors or in cell-to-cell recognition
What can diffuse across the membrane?
Lipid soluble substances such as vitamin A, small molecules like oxygen and carbon dioxide can dissolve in the phospholipid and diffuse across the membrane
How does the phospholipid layer being hydrophobic effect diffusion is different molecules
Lipid soluble molecules move through the cell membrane more easily than water soluble substances
Name molecules that struggle to diffuse through membrane
Why is this?
Glucose, polar molecules and jk s can’t readily diffuse through the phospholipids
This is because they are water soluble
How do water soluble substances pass through the cell membrane?
They pass through intrinsic protein molecules which form water filled channels across the membrane
What is the name for a membrane that picks what to diffuse in and out
Selectively permeable membrane
Define simple diffusion
The movement of molecules or ions from a region of high concentration to lower concentration down a concentration gradient until equilibrium is reached. It is a passive process it does not require atp
Name the factors affecting simple diffusion:
- the concentration gradient (greater difference the more molecules diffuse in a given time)
- thickness of the exchange surface/distance of travel where diffusion takes place (thinner=more molecules diffuse)
- the surface area is the membrane
- size of diffusing molecules (smaller diffuses faster)
- temperature
- nature of diffusing molecules (fats diffuse faster than water soluble molecules)
Name the rate of diffusion equation:
(Surface area x difference in concentration) divided by the length of diffusion pathway
Define facilitated diffusion.
The passive transfer of molecules or ions die. A concentration gradient, across a membrane by protein carrier molecules In the membrane
Where does facilitated diffusion occur?
At a specific sit on the plasma membrane wher there are transport protein molecules (intrinsic carrier/channel proteins)
Define channel proteins in detail
Molecules with pores lines with polar groups. As the channels are hydrophilic, water soluble ions can pass through. The channels open and close according to the needs of the cell
Define carrier proteins in detail
Allow diffusion of larger polar molecules such as sugar and amino acids across the membrane. A molecule attaches to its binding site, on the carrier protein. The carrier protein changes shape and released the molecule on the other side of the membrane
Describe how larger molecules e.g amino acids diffuse through a cell membrane
A molecule attaches to the binding site, on the carrier protein. The carrier protein changes shape and releases the molecule on the other side of the membrane
Does the use of carrier proteins use ATP
No, carrier and channel proteins increase the rate of diffusion down a concentration gradient without energy in the form of ATP
Define active transport
A process in which ions and molecules move from an area of low concentration to high concentration against a concentration gradient through a semi permeable membrane, it is an active process it requires ATP
Name some features of active transport
1- ions/molecules are moved from a lower to higher concentration against a concentration gradient
2- requires energy in the form ATP. Anything that affects respiration will effect active transport
3- process occurs through intrinsic carrier proteins spanning the membrane
4-rate is limited by the number and availability of carrier proteins
Name some processes involving active transport
Muscle contraction, nerve impulse transmission, reabsorption of glucose in the kidney nephron and mineral uptake into plant root hair cells
Describe the process of ATP
1) Molecule or ion combines with a specific carrier protein on the outside of the membrane
2) ATP transfers a phosphate group to the Carrie protein on the inside of the membrane
3) carrier protein changes shape and carried the molecule across the membrane, to the inside of the cell
4) molecule is realised into cytoplasm
5) phosphate ion is released from the carrier molecule back to the cytoplasm and recombined with ADP to form ATP
6) carrier protein returns to its original shape