C1.1 -Enzymes & Metabolism Flashcards
what are enzymes
protein based biological catalyst
catalysts
increase the rate of chemical reactions
purpose of enzymes
required to speed up reactions and allow them to occur at reasonable temperatures
metabolism
sum of all the ezyme catalyzed reactions in a cell
activation energy
energy needed to destabalize bonds so reactions can occur
globular proteins
3D protein structures
induced fit model
active site in substrate specific, but not fixed shape
describe the induced fit model process
- substrate binds to active site
- active site changes shape
- affects bonding in substrate
- products are released
- active site returns to original shape
anabolic reactions
smaller to big
making bonds
condensation
requires energy
ex: photosynthesis
catabolic reactions
big to smaller
breaking bonds
hydrolysis
releases energy
ex: cell respiration (release of ATP)
role of molecular motion & collisions in catalysis
chemical reactions require collion
increasing temp/concentration increases collision rates
molecules must be in correct orientation
denaturation
permanent change to 3D structure of active site, unable to catalyze reactions
denaturing factors
temperature, pH, substrate concentration
movement of enzyme & substrate in DNA replication
enzyme to substrate
movement of enzyme & substrate in ATP synthase
substrate to enzyme
movement of enzyme & substrate in cellular reactions
enzyme and substrate move towards each other