C 1.1 Enzymes and Metabolism Flashcards
enzyme ending
-ase
anabolism
synthesis of complex molecules from simpler molecules
(condensation reaction)
catabolism
breakdown of complex molecules into simpler molecules
(hydrolisis)
EVERY reaction in a living organism is catalyzed by an enzyme! how?
by increasing the rate of reaction by lowering activation energy
describe enzymes
globular protein
has an active site where the substrate binds for catalysis (specific to substrate)
induced fit model
- substrate induces the active site of the enzyme to change shape so that there is an optimal fit between the substrate and active site
- enzyme-substrate complex is formed
- Catalysis occurs, product formed
substrate-active site collisions in enzyme catalysis
larger substrate molecules or enzymes can be immobilized resulting in increased stability, durability, and efficiency
Relationship between active site structure and enzyme-substrate specificity
the active site is similar to the shape of the enzyme, but adjusts to fit it perfectly once the complex has been made
Relationship between active site structure and denaturation
When an enzyme is denatured, the active site specificity changes, so that it can no longer bind to substrates
Catalase
Breaks down H2O2 to 2H2O + O2, killing bacteira. That’s why hydrogen peroxide is added to open wounds.