buzzwords

Question 1

Herring bodies

Answer 1

neurosecretory bodies in axons from hypothalamus in post. pituitary

Question 2

Hurthle cells

Answer 2

large epithelial cells with eosinophilic cytoplasm associated with hashimoto’s thyroiditis and follicular thyroid cancer

Question 3

Orphan Annie eye nuclei

Answer 3

nuclei that appear empty papillary thyroid carcinoma

Question 4

Zellballen

Answer 4

nest-like clusters of cells seen in neuroendocrine tumors, pheochromocytoma

Question 5

Kimmelstiel–Wilson nodules

Answer 5

glomerulosclerosis

hyaline nodules that form in the glomerulus, associated with diabetes

Question 6

Homer-Wright pseudorosettes

Answer 6

tumor cells surround a lumen in neuroectodermal tissue such as neuroblastoma

Question 7

Kernicterus

Answer 7

Seen in newborns with hyperbilirubinemia

brain damage with excessive jaundice

Question 8

Ground glass appearance –

Answer 8

Fluffy infiltrates) seen on x-ray with hyalinization of alveoli (RDS), can be associated with CMV

Question 9

Blue-dome appearance

Answer 9

bluish appearance on outside of cysts seen with fibrocystic changes

Question 10

Popcorn calcifications on mammography

Answer 10

classic description of fibroadenoma

Question 11

“Indian file” infiltration

Answer 11

invasion in single file lines seen in lobular carcinoma

Question 12

Signet Ring cells

Answer 12

large intracellular vacuole that pushes the nucleus to one side, giving the appearance of a ring with a stone on one side. Seen in lobular carcinoma

Question 13

Peau d’orange

Answer 13

Orange peel appearance of the breast seen in inflammatory carcinoma

Question 14

Moth eaten

Answer 14

Epidermis permeated by large round to ovoid cells that is seen with Paget’s disease of the breast

Question 15

Michaelis Gutmann bodies

Answer 15

dense round inclusions of the urinary tract seen in malacoplakia

Question 16

Reinke crystals

Answer 16

Intracytoplasmic rod-shaped crystals seen in Leydig cell tumors

Question 17

Schiller Duval bodies

Answer 17

perivascular structure (tumor cells lined around a vessel) that resembles a glomerulus

seen in yolk sac tumors

Question 18

Snowstorm appearance

Answer 18

Or “cluster of grapes” that is seen in hydatidiform moles

Question 19

Koliocytosis

Answer 19

Dark, large, irregular nucleus seen on cytology in cells infected with HPV

Question 20

Chocolate cyst

Answer 20

Endometrial cyst of the ovary seen with endometriosis

Question 21

Triple negative

Answer 21

Breast cancer cells that do not express ER, PR, or HER2/neu, difficult to target with therapy

Question 22

Leaf-like projections

Answer 22

Projections seen from Phyllodes tumors into the cysts

Question 23

String of pearls

Answer 23

Seen on ultrasound in polycystic ovarian syndrome as numerous follicles in ovary

Question 24

Blueberry muffin baby

Answer 24

Blue rash seen in TORCH infections and disseminated neuroblastoma

Question 25

Clue cells

Answer 25

Vaginal epithelial cells coated with gram-variable rods (Gardnerella vaginalis) due to BV

Question 26

Hutchinson’s teeth

Answer 26

Babies that have smaller, widely spaced teeth with notches are a sign of syphillis

Question 27

Owl’s eye

Answer 27

nuclear inclusion body that occurs with CMV

Question 28

Fried egg appearance

Answer 28

Clear cytoplasm with round nucleus seen in seminoma