Buzz Words Flashcards

1
Q

mechanism of action of SSRIs

A

block reuptake of serotonin into presynaptic cell

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2
Q

best SSRI in adolescents

A

fluoxetine

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3
Q

what pathway does fluoxetine block

A

CYP450

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4
Q

best SSRI in epileptics

A

citalopram

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5
Q

safest SSRI in cardiac patients

A

sertraline

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6
Q

contraindicated drugs with SSRIs

A

triptans
NSAIDS
Aspirin
Warfarin

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7
Q

mechanism of action of TCAs

A

block reuptake of serotonin + noradrenaline into presynaptic terminals

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8
Q

mechanism of action of phenelzine

A

irreversible inhibition of monoamine oxidase enzymes – slows breakdown of noradrenaline + serotonin

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9
Q

mechanism of action of moclobemide

A

reversible inhibition of monoamine oxidase enzymes – slows breakdown of noradrenaline + serotonin

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10
Q

what is phentolamine used for

A

treatment of hypertensive crisis

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11
Q

what type of drug is lofepramine and imipramine

A

TCAs

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12
Q

what type of drug is venlafaxine

A

serotonin noradrenaline reuptake inhibitor

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13
Q

mirtazapine

A

NaSSA

-antagonises adrenergic receptors + blocks serotonin receptors

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14
Q

trazodone

A

given to treat sexual dysfunction caused by SSRI

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15
Q

mechanism of action of sodium valproate

A

increases GABA

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16
Q

mechanism of action of lamotrigine

A

blocks sodium channels - decreases glutamate release

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17
Q

typical antipsychotics

A

haloperidol

chlorpromazine

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18
Q

treatment of extra pyramidal side effects

A

procyclidine

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19
Q

mode of action of galantamine + rivastigmine

A

cholinesterase inhibitors

20
Q

mode of action of memantine

A

blocks NMDA receptors

21
Q

what is a jaw jerk a sign of

A

frontal cognitive syndrome

22
Q

confusion, ataxia, ophthalmoplegia

A

thiamine deficiency

23
Q

which area has strongest association with addiction

A

septal area

24
Q

problem with broccas area

A

expressive aphasia

25
Q

problem with wernicke area

A

receptive aphasia

26
Q

trisomy 18

A

Edwards syndrome

27
Q

IQ 70-84

A

Borderline learning disability

28
Q

IQ 50-69

A

mild learning disability

29
Q

IQ 35-49

A

moderate learning disability

30
Q

IQ 20-34

A

severe learning disability

31
Q

IQ <20

A

profound learning disability

32
Q

PHQ-9 score

A

used to assess severity of depression

33
Q

SADPERSONs

A

used to calculate suicide risk

34
Q

oculogyric crisis

A

example of a dystonic reaction, involuntary prolonged upward deviation of the eyes

35
Q

torticollis

A

example of a dystonic reaction- asymmetrical head/neck position

36
Q

patient with alcohol dependence ‘staggering, confused, restricted eye movements’

A

wernicke’s encephalopathy

37
Q

Korsakoff syndrome

A

patient acting strange, confabulating, short term memory problems

38
Q

1st line for alcohol dependence relapse prevention

A

naltrexone

39
Q

mode of action of naltrexone

A

opioid antagonist - reduces reward from alcohol

40
Q

mode of action of acamprostate

A

acts of glutamate + GABA systems to decrease cravings

41
Q

mode of action of disulfiram

A

inhibits acetaldehyde dehydrogenase

42
Q

opioid overdose therapy

A

naloxone

43
Q

dialectical behavioural therapy

A

borderline PD

44
Q

Tx of Parkinson’s induced psychosis

A

clozapine

45
Q

Tx of Parkinsons induced dementia

A

rivastigmine