Burns & Oncology Flashcards

1
Q

Burns ________ capillary permeability and ______ seeps out into the tissue.

A

increase

plasma

The majority of this occurs in the first 24 hrs and we need to worry about shock.

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2
Q

Burn victimes are in ____. The pulse _____. CO _____. UOP ____.

A

FVD due to massive fluid shifts bc the capillaries are leaking

pulse increases (compensation for lack of fluid in vascular space)

CO decreases (less volume less pressure)

UOP decreases (kidneys are either trying to hold on to flui or aren’t being perfused)

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3
Q

What all is secreted with burn victims?

A

Epinephrine and norepinephrine to make you peripherally vasoconstrict to shunt.

ADH and Aldosterone hold on to sodium and water to increase blood volume.

ADH just water.
Aldosterone water and sodium.

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4
Q

Anytime the ______ BP drops below __ the client will not have what?

A

Anytime the systolic BP drops below 90 the client will not have adequate organ perfusion.

ex. 85/60

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5
Q

Rule of 9’s

A

Measures % of BSA that is burned.

Head and Neck: 9%

Front of Truck: 18%
Back of Torso: 18%

Arm: 9% each
- Ex. Anterior arm: 4.5%

Leg: 18% each

Genital area: 1%

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6
Q

Partial-thickness burns vs. Full-thickness burns

A

Partial - first and second degree

Full - third and fourth

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7
Q

Examples of severe burns:

A

located on face, neck, or chest = interferes with breathing

hands, feet, joints, eyes = interferes with daily life

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8
Q

Risk Factors with Burns:

A

Heart, lung, kidney disease (less able to compensate or go without perfusion)

Healing issues (pre-existing diabetes or peripheral vascular disease)

Other injuries (falls, smoke inhalation)

Old and very young

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9
Q

A higher mortality is expected in ______ & ______ with burns. Why?

A

very young and very old

Skin is very thin and they have less subQ fat meaning burns can go deeper.

BSA is a lot less in the very young.

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10
Q

Treatment for Burns:

A

Stop burning process (blankets, cool water)
——- blankets hold in body heat and keep out germs.

Remove jewelry and non-adherent clothing and cover with dry clean cloth.

Check for inhalation injuries and treat

  • —– Carbon Monoxide - oxygen 100%
  • —– Hydrogen cyanide - oxygen 100%
  • ———– if you suspect inhalation injury = intubate BEFORE swelling occurs

Fluid replacement (LR and albumin)

Medication (albumin, opioids, tetanus toxoid, immune globulin

Infection Control (systemic antibiotics / topical meds)

Wound Care (debridement / grafting

Nutrition (protein and vit. C)

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11
Q

Carbon Monoxide Poisoning

A

Client will be hypoxic even with O2 sat measuring 100%.

treatment is 100% oxygen

watch for signs of hypoxia, not the O2 sat because it only counts bound hemoglobin, not hemoglobin boung specifically with oxygen.

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12
Q

Hydrogen cyanide

A

treatment 100% oxygen

antidote at hospital

determine if the burn occurred in an open or closed space

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13
Q

Indicators of inhalation injury:

A
singed nose or facial hair
soot on face
coughing up secretions with dark specks
dysphagia
wheezing
blisters found on oral / pharyngeal mucousa
hoarseness
substernal / intercostal retractions and stridor 

** if you see these, intubate in case their airway swells shut

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14
Q

Fluid Replacement with Burns:

A

Needs at least 2 large bore IV’s.

Crystalloids (LR) and colloids (albumin) are used for fluid replacement

Based on time injury occurred.

  • – total amount of fluid needed for first 24, then give half in first 8 hours.
  • – (2-4 mL of LR) x (kg) x (TBSA%) = total fluid requirements in first 24 hrs
    • 4 mL used for electrical burns to prevent renal damage
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15
Q

How do you tell if fluid replacement in burn victims is adequate?

A

measure urinary output

min of 0.5 to 1 mL/hg/hr (30-50 mL/hr)

75-100 mL/hr for electrical injuries

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16
Q

Restless burn victim? Think:

A

pain

hypoxia

inadequate fluid replacement

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17
Q

Albumin

A

colloid

  • administered after first 24 hrs once capillary permeability is normal
  • Helps to hold onto fluid in vascular space
  • increases vascular volume which increases renal perfusion, BP, and CO
  • increases workload of heart bc it’s increasing volume
  • WATCH FOR FVE / you’ll know if the CO begins to decrease, you hear crackles or wetness in the lungs
  • Measure CVP hourly to ensure you’re not overloading the client!
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18
Q

Why do we give IV pain meds to burn victims?

A

It’s faster!

IM won’t work if the muscle is damaged or not being perfused.

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19
Q

Immunizations with burns.

A

Tetanus Toxoid (active immunity) –> takes 2-4 wks to develop immunity

Immune globulin (passive immunity) –> immediate protection

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20
Q

Infection control with burns

A

Systemic Antibiotic Therapy

Topical Medications

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21
Q

Systemic Antibiotic Therapy with Burns

A

broad-spectrum avoided (superinfection, secondary infection, sepsis)

    • broad-spectrum used until wound cultures return.
    • COLLECT CULTURES BEFORE ADMINISTERING ANTIBIOTICS

-mycin durgs –> watch for BUN and creatinine increases (nephrotoxicity)
and for hearing loss (ototoxicity)

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22
Q

Topical Meds and Burns

A

Why? Reduced blood flow = IV meds may not get to tissues

Silver dressings are antimicrobial.
Left in place for 3-14 days

1) mafenide acetate - acid/base problems likely / stings / reapply if it rubs off
2) silver nitrate - keep wet / electrolyte problems likely
3) antimicrobial ointments - antibacterial coverage / promote moist wound

alternate methods so tolerance isn’t developed

*CHECK FOR SULFATE ALLERGY

How to apply? Thin layer w sterile gloves

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23
Q

Debridement

A

1 ) enzymatic debridement

  • —- sutilains or collagenase eat dead tissue
  • ——- don’t use on face (scarring)
  • ——- don’t use if pregnant
  • ——- don’t use over large nerves
  • ——- don’t use if open to body cavity

2 ) hydrotherapy

  • —- pain management before this therapy
  • —- immersion hydrotherapy (whirlpool) can cause cross-contamination bt injuries
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24
Q

Grafting

A

Autograft = own

surgeon can re-harvest from same donor site every 12-14 days

blue or cool skin graft = poor circulation
—- may use syringes or pressure to try and work any fluid or air out from under graft to help w adherence

Graft = cover w wet NS gauze
Donor site = dry gauze

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25
Nutrition and burn victims
more caloric intake needed should start 1-2 days postburn PROTEIN & VITAMIN C to promote healing Check Pre-Albumin to check for proper nutrition --- pre = more sensitive lab
26
Complications w Burns
Circulation Renal system (watch for renal failure / anuria / FVE) Electrolyte imbalances GI system (stress ulcer / paralytic ileus / ascites) Contractures Infection
27
Circulation and Burns
Circ. Check: cap refill / pulses / color / temp Elevation can reduce swelling. escharotomy & fasciotomy - relieves pressure and restores circulation fasciotomy is deeper
28
What is the renal system going to do in burn pts?
kidneys will try to retain fluid (or are not being perfused) ----- this means you may put in catheter and get no urine return or see brown or red urine Mannitol can be used to flush out kidneys. When urine is clear, d/c drug. anuria or oliguria = renal failure After 48 hours, client will begin urinating again. Fluid is going back into vascular space (cap permeability normalizes / albumin pulls fluid into vasculature again) NOW we worry about FVE and NEED kidneys to increase output.
29
Will potassium be high or low in burn victims?
HIGH! Potassium is stored inside of cells, so when cells rupture, it leaks into the blood.
30
What is prescribed to treat stress ulcers?
magnesium carbonate pantoprazole (protonix) famotidine (Pepcid)
31
Another name for stress ulcer
curling's ulcer
32
Antacids
aluminum hydroxide gel magnesium hydroxide (milk of magnesia)
33
H2 Antagonists
famotidine (pepcid) nizatidine
34
Why do we have burn client NPO w NG tube hooked to suction?
prevent paralytic ileus * decreased vascular volume (GI is not gonna be perfused) * decreased GI motility * Hyperkalemia ===we don't want food sitting in GI tract and rotting with NG feedings CHECK RESIDUALS to make sure its moving
35
Client w burn doesn't have bowel sounds. What will happen?
increased abdominal girth / ascites
36
Burn pt with NG tube will have it removed when?
we hear bowel sounds
37
How to prevent contractures w burn pts
wrap each finger separately splints hyperextend neck (no pillows)
38
Chemical Burns
remove chemical and flush for 15-30 min w cool water or sterile saline brush powder chemicals off first and then flush
39
electrical burns
2 wounds (entrance & exit) First thing is continuous heart monitoring for 24 hrs. At risk for V. FIB myoglobin and hemoglobin can build up and cause renal damage amputations common bc circulatory system is wrecked. Other complications: cataracts, gait problems, neuro deficit.
40
What is the number one cause of preventable cancer?
tobacco
41
suspected dietary causes of cancer
low fiber diet (low residue) increased red meat increased animal fat nitrites (processed sandwich meats) alcohol preservatives and additives
42
Risk Factors of Cancer
``` tobacco alcohol dietary causes --- low fiber diet --- increased red meat and animal fat --- nitrites (processed sandwich meat) --- alcohol --- preservatives and additives obesity physical inactivity poor nutrition immunosuppressed AA hereditary UV radiation carcinogens (diesel, exhaust, asbestos) stress chronic irritation (smoking, GERD) hx of cancer or chemotherapy ```
43
Primary prevention for cancer
``` no smoking exercise good nutrition normal body wt limit alcohol vaccines for preventable (HPV and hep. B) avoid known carcinogens sunscreen ```
44
What two cancers can be prevented by vaccines?
HPV and Hepatitis B
45
Secondary Prevention Methods for Cancer (female)
monthly breast exams (day 7 through 12 of the menstrual cycle / right when period is about to end) Clinical breast exams every year greater than age 40. (every 3 yrs for 20-39) mammogram annually at 40 (no lotions, powder, deodorant) pap swears starting at 21 and every 3 yrs colonoscopy at 50 and every decade after test for blood in stool yearly starting at 50
46
Secondary Prevention Methods for Cancer (male)
``` yearly clinical testicular exams monthly testicular self-exams digital rectal exam at age 50 colonoscopy at 50 and every decade after fecal occult blood testing yearly after 50 ```
47
S/sx of cancer
``` CAUTION C - change in bowel / bladder habits A - a sore that does not heal U - unusual bleeding / discharge T - thickening or lump in breast etc. I - indigestion or difficulty swallowing O - obvious change in wart or mole N - nagging cough or hoarsness ``` anemia, leukopenia, thrombocytopenia --> bone marrow cancers unexplained weight loss --> cachexia (extreme wasting and malnutrition) fever --> blood cancers and lymphoma fatigue (due to anemia / #1 symptom) pain
48
Blood Tests with Cancer
``` Abnormal CBC and differential ---- worry about NEUTROPHIL count Elevated liver enzymes (AST and ALT) ---- increases if liver is damaged Tumor markers (biomarkers) ```
49
Positive Diagnostic Studies
``` Chest X-ray CT scan MRI PET scan Bone marrow biopsy tissue biopsy imaging studies ```
50
Types of Cancer Treatment
Surgery (curative surgery & reconstructive surgery) Radiation therapy - - Internal Radiation (brachytherapy) - - External Radiation (teletherapy, external beam radiotherapy)
51
Why is surgery a treatment for cancer?
Prevention (removing pre-cancerous or benign masses) Diagnosis (staging, biopsy, lymph node mapping) Treatment (removal of tumor)
52
Total laryngectomy. What is it? And how do we care for it post op?
removal of vocal cords, epiglottis, and thyroid cartilage Since the whole larynx is removed (including epiglottis) they will have a permanent tracheostomy o. Position post op? sitting up / semi-fowlers NG feedings to protect suture line (don't want peristalsis) monitor drains watch for carotid artery rupture or rupture of innominate artery (bleeds from trach) ---- if this happens, send back to surgery (emergency) frequent oral care NPO so watch for pneumonia bib for trach to act as a filter (keep powder away from trach) humidified environments help decrease secretions --- all breathing is done through stoma
53
How does a client with total laryngectomy talk?
special devices (electrolarynx or blom-singer) Can't whistle, can't drink through straw, not recommended to smoke or swim.
54
Post op care following a mastectomy What about if lymph nodes were removed?
bleeding --> check dressings front and back (pooling) if reconstructive surgery uses their own tissue, they will have abdominal surgical site Hemovac or Jackson Pratt drains encourage use of that arm (brushing hair, squeeze tennis balls, wall climbing, flex and extend to promote circulation) * *If lymph nodes were removed: - - avoid procedures on affected arm for the rest of their LIFE - ---- no constriction (BP, tight sleeves, watch, or purses on that side) - ---- no IV or injections - ---- wear gloves when gardening, watch small cuts, no nail-biting and no sunburn
55
Two types of Radiation Therapy
Internal Radiation (brachytherapy) External Radiation (teletherapy, external beam radiotherapy)
56
Internal Radiation (bracytherapy)
gets radiation close to the cancer or target tissue internal radiation = INSIDE body emits radiation and is a hazard to others for a time It can be sealed or unsealed General Precautions: time, distance, shielding
57
Unsealed vs. Sealed or solid
Unsealed: client and body fluids emit radiation - radioisotope given IV or PO - radioactive for 24 to 48 hours Sealed or solid: client emits radiation; body fluids are not radioactive - temporary or permanent implants placed close to tumor - ex. prostate cancer = implantable seeds cervical cancer = vaginal implant
58
Precautions with Internal Radiation
nursing assignments rotated daily nurse should only have 1 client with radiation implant at a time private room film badge (tells you how much radiation you're getting) limit visitors to 30 min/day at 6 ft away - -- no visitors less than 16 yrs - -- no pregnant visitors / nurses mark room with instructions on isotope wear gloves
59
How can you help prevent dislodgment of the implant?
keep client on bedrest decrease fiber in diet prevent bladder distention
60
You see an implant become dislodged and you see it, what do you do?
gloves, use forceps to pick up dislodged implant, place in lead-lined container, leave in room, call radiation department
61
Should patient with internal radiation sleep in same bed as their spouse? Use public transportation? Return to work immediately? Share utensils or cook for others? Only have to flush once after using bathroom?
no to all
62
External radiation
teletherapy / external beam radiation beam of high energy delivered OUTSIDE of body client is NOT radioactive don't wash off, use lotion, or get sun exposure on markings for 1 year
63
Side effects of external radiation
limited to exposed tissues erythema (redness) shedding of skin fatiuge pancytopenia (all blood components are decreased)
64
Full Chemotherapy Precautions
chemotherapy gown - must be coated to prevent contamination / change immediately two pairs of chemotherapy gloves that are thicker and longer than standard (one under gown, one over gown cuff) goggles / mask if splashing or inhalation can occur
65
Chemotherapy is excreted for ______ days after administration.
3 to 7 days wear two pairs of gloves and a chemotherapy gown (face shield if splashing)
66
disposal of chemotherapy
yellow, rigid chemotherapy waste container used for sharps and IV equipment yellow chemotherapy waste bag used for gowns, gloves, disposables wash w soap and water after removing gloves
67
What to do if a chemo spill occurs?
wash hands w soap and water get spill kit from wall in clients room put on respirator mask put on chemotherapy gown put on 2 sets of gloves put on goggles use absorbent pads to wipe up spill
68
Major complications with chemotherapy
Extravasation (vesicant is chemo drug that causes necrosis if infiltrated) - s/sx of extravasation - pain, swelling, no blood return - stop infusion ASAP / stay with client / send for extravasation kit
69
Transplants
Bone marrow and stem cell transplants are used for hematologic cancers. Stem Cell Transplant --> stem cells transplanted from blood stream Bone Marrow Transplant --> stem cells transplanted from bone marrow *stem cells are given IV and settle into bones later
70
GI Side Effects of Cancer and/or Cancer Treatment
N/V - most common after tx / esp 24-48 hrs after treatment * ondansetron (serotonin receptor antagonists) given for first wk after chemo * netupitant / palonosetron (prevents acute and delayed N/V) only one dose / one pill / one hour before chemo * ginger, aromatherapy, acupuncture, acupressure, distraction, relaxation Stomatitis - oral cavity irritation Diarrhea - nutrition and F&E imbalances
71
Integumentary Side Effects of Cancer and/or Cancer Treatment
alopecia mastectomy, amputation, scar they need to look at the incision
72
Hematopoietic System - Side Effects of Cancer and/or Cancer Treatment
bone marrow is supressed (decreased RBCs, WBCs, and platelets) client is at risk for anemia, infection, and bleeding Infection is #1 cause of cancer related deaths
73
General Side Effects of Cancer and/or Cancer Treatment
``` N/V stomatitis diarrhea alopecia scar suppressed bone marrow (decreased RBCs, WBCs, and platelets) fatigue pain ``` ***client at risk for anemia, infection, and bleeding
74
Precautions to Prevent Infection in Cancer Patients
private room / limit visitors and nurses client has own supplies change dressings and IV tubing daily cough and deep breath to prevent pneumonia no gardening or cleaning up after pets avoid crowds, wear mask handwashing (after touching any animal) drink only fresh water avoid uncooked foods (meats, eggs) brush teeth w soft toothbrush 4 times a day no alcohol-based mouthwash report temp 100.4 or higher ``` **** if neutropenic *** prescribe antibiotics VS q4hrs private room w door closed antimicrobial soap no invasive procedures (IM, rectal) Avoid catheters or NG tubes limit acetaminophen ```
75
Life-Threatening Complications of Cancer and/or Treatments
Neutropenia (tx w antibiotics and neutropenic precautions) DVTs (2nd leading cause of death) Thrombocytopenia
76
How to calculate Neutropenia
ANC - absolute neutrophil count 2500 - 8000 cells/mm is normal
77
Why are DVT's prevalent in cancer patients?
``` prolonged bedrest surgery use of central line external compression of vessels by tumor invasion of vessels by tumor certain chemo drugs ``` DVT's can lead to PE
78
Thrombocytopenia in Cancer pts
decrease in platelets = bad clotting = bleed risk you can give platelets
79
Risk factor for Thrombocytopenia
``` advanced metastatic disease hematological malignancies bleeding disorders (hemophilia, liver dz, ITP - idiopathic thrombocytopenia purpura) bacterial infections anticoagulant meds result of cancer treatments ```
80
Thrombocytopenia Assessment
``` Hx VS pulse oximetry change in LOC (headache, pupil changes, anything that makes you suspect intracranial bleed) conjunctival hemorrhages petechiae, ecchymosis, purpura oozing bleeding from rectum, ears, nose, mouth ```
81
How to infuse Platelets?
never infuse them cold bc the spleen will reject them
82
RBC transfusions are for clients with ?
symptomatic anemia don't want Hgb/Hct to drop below 8g/dL and 24%